Pulmonary function in survivors of Wilms' tumor

Journal Article · Mon Apr 01 04:00:00 EST 1991 · Pediatric Hematology and Oncology; (United States)

DOI:https://doi.org/10.3109/08880019109033440· OSTI ID:5186525

Shaw, N J; Eden, O B; Jenney, M E; Stevens, R F; Morris-Jones, P H; Craft, A W; Castillo, L ^[1]

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1. Royal Hospital for Sick Children, Edinburgh (Scotland)

The respiratory status of 47 patients surviving childhood Wilms' tumor was studied. The group that had received flank irradiation (which impinges on the lower lung) (n = 17) had a significantly lower mean percent predicted for forced expiratory volume in one second, residual volume, and total lung capacity when compared to those who had received no irradiation (n = 23). Those patients who had received whole-lung irradiation (n = 3) had significantly lower transfer factor for carbon monoxide and gas transfer per unit lung volume when compared to the nonirradiated group (n = 23). There was no significant difference in the prevalence of respiratory symptoms between the three groups. Patients receiving any form of radiotherapy for Wilms' tumor may have abnormalities of pulmonary function and should have pulmonary function tests performed as part of their long-term follow-up.

• OSTI ID: 5186525
• Journal Information: Pediatric Hematology and Oncology; (United States), Journal Name: Pediatric Hematology and Oncology; (United States) Vol. 8:2; ISSN PHONE; ISSN 0888-0018
• Country of Publication: United States
• Language: English

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