Kinetic analysis of dynamic PET data
Our goal is to quantify regional physiological processes such as blood flow and metabolism by means of tracer kinetic modeling and positron emission tomography (PET). Compartmental models are one way of characterizing the behavior of tracers in physiological systems. This paper describes a general method of estimating compartmental model rate constants from measurements of the concentration of tracers in blood and tissue, taken at multiple time intervals. A computer program which applies the method is described, and examples are shown for simulated and actual data acquired from the Donner 280-Crystal Positron Tomograph.
- Research Organization:
- Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States)
- DOE Contract Number:
- AC03-76SF00098
- OSTI ID:
- 5178278
- Report Number(s):
- LBL-17313; ON: DE84008165
- Resource Relation:
- Other Information: Portions are illegible in microfiche products. Thesis
- Country of Publication:
- United States
- Language:
- English
Similar Records
Image-derived and arterial blood sampled input functions for quantitative PET imaging of the angiotensin II subtype 1 receptor in the kidney
Dipyridamole-induced stress - variability in {sup 82}Rb PET kinetic studies in the anesthetized canine
Validity of PET studies in brain tumors
Journal Article
·
Sun Nov 15 00:00:00 EST 2015
· Medical Physics
·
OSTI ID:5178278
+4 more
Dipyridamole-induced stress - variability in {sup 82}Rb PET kinetic studies in the anesthetized canine
Journal Article
·
Wed May 01 00:00:00 EDT 1996
· Journal of Nuclear Medicine
·
OSTI ID:5178278
Validity of PET studies in brain tumors
Journal Article
·
· Cerebrovascular and Brain Metabolism Reviews; (USA)
·
OSTI ID:5178278
Related Subjects
62 RADIOLOGY AND NUCLEAR MEDICINE
POSITRON COMPUTED TOMOGRAPHY
COMPUTER CALCULATIONS
MATHEMATICAL MODELS
ANTIMETABOLITES
COMPUTER CODES
NUMERICAL ANALYSIS
COMPUTERIZED TOMOGRAPHY
DIAGNOSTIC TECHNIQUES
DRUGS
EMISSION COMPUTED TOMOGRAPHY
MATHEMATICS
TOMOGRAPHY
550601* - Medicine- Unsealed Radionuclides in Diagnostics
POSITRON COMPUTED TOMOGRAPHY
COMPUTER CALCULATIONS
MATHEMATICAL MODELS
ANTIMETABOLITES
COMPUTER CODES
NUMERICAL ANALYSIS
COMPUTERIZED TOMOGRAPHY
DIAGNOSTIC TECHNIQUES
DRUGS
EMISSION COMPUTED TOMOGRAPHY
MATHEMATICS
TOMOGRAPHY
550601* - Medicine- Unsealed Radionuclides in Diagnostics