Exposure to well water and pesticides in Parkinson's disease: a case-control study in the Madrid area
- Department of Neurology, Hospital General Gregorio Maranon, Madrid, (Spain)
Past exposure to well water and pesticides was assessed in 128 unselected Parkinson's disease (PD) patients and 256 age and sex-matched controls. All were residents in a defined urban area of Madrid, Spain. In keeping with other reports, we found that exposure to well water might be a factor associated with the likelihood of developing PD, though only prolonged exposures of 30 years or longer were significantly different between PD and controls (p less than 0.02). In contrast, past exposure to pesticides did not appear to be associated with an increased risk of developing PD. Prolonged well water drinking antedating the development of PD was not associated with early onset of the disease, nor did such cases progress to greater disability. Future case-control studies addressing prolonged well water consumption as a risk factor in PD should look for differences in the content of substances other than pesticides in the water as determined by the source of water to which patients may have been specifically exposed.
- OSTI ID:
- 5174875
- Journal Information:
- Movement Disorders; (United States), Vol. 7:2; ISSN 0855-3185
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
NERVOUS SYSTEM DISEASES
EPIDEMIOLOGY
PESTICIDES
HEALTH HAZARDS
SPAIN
WATER POLLUTION
WATER WELLS
CONTAMINATION
MAN
RISK ASSESSMENT
ANIMALS
DEVELOPING COUNTRIES
DISEASES
EUROPE
HAZARDS
MAMMALS
POLLUTION
PRIMATES
VERTEBRATES
WELLS
560300* - Chemicals Metabolism & Toxicology