Biochemical changes during nutrition with zinc deficient diet

Conference · Fri Mar 15 04:00:00 EST 1991 · FASEB Journal (Federation of American Societies for Experimental Biology); (United States)

OSTI ID:5174062

Slavik, M; Wu, J; Slavik, J ^[1]

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1. Univ. of Kansas, Wichita (United States)

This paper presents biochemical changes following a Zn deficient diet (ZDD). Five NZW rabbits of both sexes, weighing 3-3.5 kg were kept for 2 wks on a standard diet (SD) which was replaced by the ZDD. After 16 weeks ZDD was switched back to SD. Blood samples were collected in metal free containers after overnight fast. Atomic absorption and enzymatic assays were used for the analysis of trace metals and pyridoxal phosphate (PP), resp. A significant (S) decrease of serum Zn was seen during the ZDD, followed by an increase above normal values during the repletion period (RP). The serum Zn levels before, at the end and 1 week after the depletion were 173.8 {plus minus} 24.2, 82.2 {plus minus} 0.95 and 278.7 {plus minus} 33.0 {mu}g%, resp. Serum Cu increased during the ZDD and then returned to normal, while the serum Mg did not change. Serum PP decreased on the ZDD and returned to normal during the RP. These results indicate a S decrease of serum Zn during the ZDD followed by a rebound during the RP. They suggest a linkage of Zn depletion to other biochemical changes.

• OSTI ID: 5174062
• Report Number(s): CONF-9104107--
• Conference Information: Journal Name: FASEB Journal (Federation of American Societies for Experimental Biology); (United States) Journal Volume: 5:5
• Country of Publication: United States
• Language: English

Related Subjects

560300* -- Chemicals Metabolism & Toxicology
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ABSORPTION SPECTRA
ANIMALS
BIOLOGICAL EFFECTS
BLOOD SERUM
DIET
ELEMENTS
MAMMALS
METABOLISM
METALS
NUTRITIONAL DEFICIENCY
RABBITS
SPECTRA
VERTEBRATES
ZINC