Value of mammography screening in women under age 50 years

Journal Article · Fri Mar 11 04:00:00 EST 1988 · JAMA, J. Am. Med. Assoc.; (United States)

DOI:https://doi.org/10.1001/jama.1988.03720100030034· OSTI ID:5168233

Eddy, D M; Hasselblad, V; McGivney, W; Hendee, W

Two quantitative methods, Confidence Profiles and CAN*TROL, are used to analyze evidence and estimate the health and economic consequences of adding annual mammography to annual breast physical examinations in asymptomatic women aged 40 to 49 years who are at average risk for breast cancer. Such women have about a 128 in 10,000 chance of having breast cancer in the next ten years and about an 82 in 10,000 chance of dying of such a cancer. Adding annual mammograms to annual breast physical examinations each year during that age decade would reduce the probability of death to about 60 in 10,000, a reduction of about 26%. Screening would increase the expected lifetime of a woman destined to get breast cancer between ages 40 and 49 years by about 3.5 years. Ten years of screening with mammography in that age decade carries a risk of radiation-induced cancer of about one in 25,000 and a risk of a surgery recommendation for a lesion that is not cancer of about one in ten. If 25% of the women in this age group in the United States were screened every year, breast cancer mortality in the year 2000 would be decreased by about 373 deaths. In 1984 dollars, the cost of screening, workups, and continuing care in the year 2000 would be about $408 million. Treatment costs would be decreased by about $6 million, leaving a net increase in costs in the year of 2000 of approximately $402 million (1984 dollars).

• Research Organization: Duke Univ., Durham, NC (USA)
• OSTI ID: 5168233
• Journal Information: JAMA, J. Am. Med. Assoc.; (United States), Journal Name: JAMA, J. Am. Med. Assoc.; (United States) Vol. 259:10; ISSN JAMAA
• Country of Publication: United States
• Language: English

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560151* -- Radiation Effects on Animals-- Man
62 RADIOLOGY AND NUCLEAR MEDICINE
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
AGE DEPENDENCE
ANIMALS
BIOMEDICAL RADIOGRAPHY
BODY
COST ESTIMATION
DIAGNOSTIC TECHNIQUES
DISEASES
FEMALES
GLANDS
MAMMALS
MAMMARY GLANDS
MAN
MATHEMATICS
MEDICINE
NEOPLASMS
NORTH AMERICA
NUCLEAR MEDICINE
ORGANS
PRIMATES
RADIOINDUCTION
RADIOLOGY
RISK ASSESSMENT
SCREENING
SIDE EFFECTS
STATISTICS
USA
VERTEBRATES
WOMEN