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Diagnostic accuracy of indium-111 platelet scintigraphy in identifying left ventricular thrombi

Journal Article · · Am. J. Cardiol.; (United States)
This study defines the optimum imaging time window after injection of labeled platelet suspension for detection on left ventricular (LV) thrombi, identifies the most useful imaging views, and determines the reproducibility of this technique. A total of 662 images obtained from 64 patients were analyzed retrospectively on 2 separate occasions by 3 observers blinded as to patient identity, view (right anterior oblique, anterior, left anterior oblique, and left lateral), and time after injection of the platelet suspension that the images were obtained (0 to 2, 3 to 4, and 5 to 6 days). Images were categorized as either positive or negative. In every case surgical or autopsy verification of the presence or absence of LV thrombus was possible. It was concluded that (1) indium-111 platelet scintigraphy is a reproducible and specific technique for identifying LV thrombus, and (2) we advise imaging on day 0 and again 3 to 4 days after injection of the platelet suspension in right anterior oblique, left anterior oblique, left lateral, and anterior views to maximize accuracy and to facilitate localization of LV thrombus.
Research Organization:
Univ. of Oklahoma Medical School, Oklahoma City
OSTI ID:
5128363
Journal Information:
Am. J. Cardiol.; (United States), Journal Name: Am. J. Cardiol.; (United States) Vol. 51:10; ISSN AJCDA
Country of Publication:
United States
Language:
English