Kit for preparing a technetium-99m myocardial imaging agent
This patent describes a kit for preparing a technetium 99m myocardial imaging agent. It comprises a first vial containing a lyophilized pyrogen free, sterile mixture of an effective reducing agent and a first ligand having the following general formula: wherein the R{sub 1} groups may be the same or different and are selected from the group consisting of hydrogen, hydroxy, C{sub 1} - C{sub 5} alkyl, C{sub 1} - C{sub 5} alkyl substituted by hydroxyl, ether, ester, amide, ketone, aldehyde and nitrile; the R{sub 2} groups may be the same or different and are selected from the group consisting of hydrogen, hydroxy, C{sub 1} - C{sub 5} alkyl, C{sub 1} - C{sub 5} alkyl substituted by hydroxyl, ether, ester, amide, ketone, aldehyde, and nitrile; the X and Y groups may be the same or different and are selected from the group consisting of oxygen and sulfur; and n is equal to 1 or 2; and a second vial containing a lyophilized pyrogen free, sterile protected salt of a phosphine ligand.
- Assignee:
- Mallinckrodt Medical, Inc., St. Louis, MO (United States)
- Patent Number(s):
- A; US 5112594
- Application Number:
- PPN: US 7-680446
- OSTI ID:
- 5127380
- Country of Publication:
- United States
- Language:
- English
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62 RADIOLOGY AND NUCLEAR MEDICINE
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BODY
CARDIOVASCULAR SYSTEM
CHEMICAL PREPARATION
COUNTING TECHNIQUES
DIAGNOSTIC TECHNIQUES
DIAGNOSTIC USES
HEART
HOURS LIVING RADIOISOTOPES
INTERMEDIATE MASS NUCLEI
INTERNAL CONVERSION RADIOISOTOPES
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
LABELLED COMPOUNDS
NUCLEI
ODD-EVEN NUCLEI
ORGANS
RADIOISOTOPE SCANNING
RADIOISOTOPES
SCINTISCANNING
SYNTHESIS
TECHNETIUM 99
TECHNETIUM ISOTOPES
USES
YEARS LIVING RADIOI