Effects of cadmium ingestion and food restriction on energy metabolism and tissue metal concentrations in mallard ducks

Journal Article · Thu Aug 01 00:00:00 EDT 1985 · Environ. Res.; (United States)

DOI:https://doi.org/10.1016/0013-9351(85)90125-2· OSTI ID:5119140

Di Giulio, R T; Scanlon, P F

The single and combined effects of cadmium ingestion and food restriction were examined in a 42-day experiment with male, juvenile mallard ducks. A 2 x 3 factorial design was employed consisting of two levels of food supply (ad libitum and 55% of ad libitum intake) and three levels of cadmium in the food (0, 5 or 50 ..mu..g Cd/g food). Cadmium ingestion alone had no effect on body or tissue weights, liver glycogen, plasma concentrations of glucose, urea, uric acid, nonesterified fatty acids (NEFA), triiodothyronine (T/sub 3/), thyroxine (T/sub 4/), or plasma or adrenal concentrations of corticosterone. The food restriction resulted in reduced body weights and reduced weights of livers, kidneys, and testes, increased adrenal weights, reduced liver glycogen, increased plasma NEFA concentrations, reduced plasma T/sub 3/ and T/sub 4/ concentrations, and increased adrenal corticosterone concentrations. In combination with the food restrictions, cadmium ingestion further reduced plasma T/sub 3/ concentrations and a similar trend was noted for T/sub 4/. Additionally, the highest plasma NEFA concentrations and highest plasma and adrenal concentrations of corticosterone were observed in food-restricted ducks receiving the highest level of dietary cadmium. These results suggest that ability of cadmium ingestion to enhanced food restriction-induced alterations in energy metabolism at levels of dietary cadmium that are by themselves without apparent effect. Also, cadmium ingestion resulted in increased kidney concentrations of copper and zinc: this effect on kidney zinc concentrations was increased in food-restricted ducks.

• Research Organization: Duke Univ., Durham, NC
• OSTI ID: 5119140
• Journal Information: Environ. Res.; (United States), Vol. 37:2
• Country of Publication: United States
• Language: English

Related Subjects

63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
CADMIUM
TOXICITY
COPPER
METABOLISM
DIET
BIOLOGICAL EFFECTS
ZINC
BIOLOGICAL STRESS
DUCKS
EXPERIMENTAL DATA
NUTRITION
WEIGHT
ANIMALS
BIRDS
DATA
ELEMENTS
FOWL
INFORMATION
METALS
NUMERICAL DATA
TRANSITION ELEMENTS
VERTEBRATES
560305* - Chemicals Metabolism & Toxicology- Vertebrates- (-1987)