Thallium-201 myocardial imaging before and after coronary revascularization: assessment of regional myocardial blood flow and graft patency

Journal Article · Tue Nov 01 04:00:00 EST 1977 · Circulation; (United States)

DOI:https://doi.org/10.1161/01.CIR.56.5.830· OSTI ID:5115130

Ritchie, J L; Narahara, K A; Trobaugh, G B; Williams, D L; Hamilton, G W

Twenty patients underwent myocardial imaging with thallium-201 (/sup 201/Tl) before and subsequent to coronary artery bypass grafting. All patients had rest and maximal treadmill exercise imaging postoperatively. Eleven of the 20 patients had rest and exercise /sup 201/Tl images preoperatively; 9/20 only had rest imaging preoperatively. Postoperative regional exercise perfusion was improved in seven of the 11 patients who had preoperative exercise images, and was associated with regional graft patency in each case. Thirteen of 20 patients showed no new defect with postoperative exercise imaging. The remaining seven patients developed or had an increased defect with exercise. The patients with no new perfusion defects during postoperative study had 26/30 grafts patent (87%). Patients developing a new perfusion defect with exercise had fewer grafts patent (7 of 13 (54%); P < 0.03). In these seven cases, a new exercise-induced defect was associated with regional graft closure or residual nonoperated disease. Knowledge of the preoperative coronary anatomy allowed the distinction between ungrafted areas and regional graft dysfunction. We conclude that preoperative and postoperative /sup 201/Tl imaging may noninvasively predict graft closure and/or improved regional perfusion with patent grafts.

• Research Organization: Univ. of Washington School of Medicine, Seattle
• OSTI ID: 5115130
• Journal Information: Circulation; (United States), Journal Name: Circulation; (United States) Vol. 56:5; ISSN CIRCA
• Country of Publication: United States
• Language: English

Related Subjects

550601* -- Medicine-- Unsealed Radionuclides in Diagnostics
62 RADIOLOGY AND NUCLEAR MEDICINE
ARTERIES
BETA DECAY RADIOISOTOPES
BLOOD FLOW
BLOOD VESSELS
BODY
CARDIOVASCULAR SYSTEM
CORONARIES
COUNTING TECHNIQUES
DAYS LIVING RADIOISOTOPES
DIAGNOSTIC TECHNIQUES
ELECTRON CAPTURE RADIOISOTOPES
GRAFTS
HEART
HEAVY NUCLEI
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
MEASURING METHODS
MUSCLES
MYOCARDIUM
NUCLEI
ODD-EVEN NUCLEI
ORGANS
PATIENTS
RADIOISOTOPE SCANNING
RADIOISOTOPES
SCINTISCANNING
SECONDS LIVING RADIOISOTOPES
THALLIUM 201
THALLIUM ISOTOPES
TRANSPLANTS