High precision Compton backscatter maps of myocardial wall dynamics. Theory and applications

Journal Article · Fri Sep 01 00:00:00 EDT 1989 · Investigative Radiology; (USA)

DOI:https://doi.org/10.1097/00004424-198909000-00003· OSTI ID:5100779

McInerney, J J; Copenhaver, G L; Herr, M D; Morris, D L; Zelis, R ^[1]

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1. Pennsylvania State Univ., Hershey (USA)

Compton backscatter imaging (CBI) is a technique that uses x-rays scattered from the closed-chest surface of the heart to obtain high frequency (5 msec) and high precision (+/- 0.1 mm SD) measurements of regional surface displacements and velocities. These measurements are acquired in a three-dimensional format that allows the reconstruction of the epicardial surface and the creation of color coded displacement and velocity maps at many time points during the cardiac cycle. Applications of the technique are shown to characterize detailed regional normal wall displacement and velocity patterns, and the significant alteration of those patterns after coronary embolization. The technique is also applied to the characterization of early diastolic wall dynamics. CBI measurements show that a brief and somewhat paradoxical inward displacement of the anterior ventricular wall occurs during early diastole in normal canines. The wall dynamics associated with this inward displacement suggest a brief collapse of the ventricle subsequent to aortic valve closure. Diastolic collapse velocities and displacements are significantly altered subsequent to coronary occlusion with mean and maximum collapse velocities decreasing by 50% and concomitant inward displacements decreasing by 40%. Data acquisition with CBI is non-invasive, does not require contrast agents or radioisotopes, and uses low irradiation levels (125 kVp, 3-5 ma). The average radiation dose to the heart for a typical study is 250 mrem, significantly lower than that of other radiation based imaging techniques.

• OSTI ID: 5100779
• Journal Information: Investigative Radiology; (USA), Vol. 24:9; ISSN 0020-9996
• Country of Publication: United States
• Language: English

Related Subjects

62 RADIOLOGY AND NUCLEAR MEDICINE
CARDIOVASCULAR DISEASES
DIAGNOSIS
HEART
BIOMEDICAL RADIOGRAPHY
DOGS
LOW DOSE IRRADIATION
RADIATION DOSES
SCATTERING
X RADIATION
ANIMALS
BODY
CARDIOVASCULAR SYSTEM
DIAGNOSTIC TECHNIQUES
DISEASES
DOSES
ELECTROMAGNETIC RADIATION
IONIZING RADIATIONS
IRRADIATION
MAMMALS
MEDICINE
NUCLEAR MEDICINE
ORGANS
RADIATIONS
RADIOLOGY
VERTEBRATES
550602* - Medicine- External Radiation in Diagnostics- (1980-)