Evaluation of the pleural malignant mesothelioma patients with the relation of asbestos exposure

Journal Article · Wed Feb 01 00:00:00 EST 1989 · Environmental Research; (USA)

DOI:https://doi.org/10.1016/S0013-9351(89)80083-0· OSTI ID:5098651

Kishimoto, T; Okada, K; Sato, T; Ono, T; Ito, H ^[1]

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1. Kure Kyosai Hospital (Japan)

There has been a recent increase in the number of patients with malignant mesothelioma in parts of Japan where Naval shipyards were located during World War II. This can be attributed to asbestos exposure during work in the shipyard. We have studied eight patients who were seen between 1984 and 1986 in Kure Kyosai Hospital. All had a history of asbestos exposure, seven in a Naval shipyard. In these seven cases, the latent period between exposure and the appearance of mesothelioma was 43-49 years. Quantification of asbestos bodies in the lung indicated a high concentration in all patients, giving further weight to the concept that asbestos is an etiologic factor in the genesis of mesothelioma. The major types of asbestos fibers were crocidolite and amosite. The study of structural features of these two types may provide a clue to the pathogenesis of the disease.

• OSTI ID: 5098651
• Journal Information: Environmental Research; (USA), Vol. 48:1; ISSN 0013-9351
• Country of Publication: United States
• Language: English

Related Subjects

63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ASBESTOS
HEALTH HAZARDS
LUNGS
NEOPLASMS
ETIOLOGY
JAPAN
LATENCY PERIOD
OCCUPATIONAL EXPOSURE
PATHOGENESIS
PATIENTS
ASIA
BODY
DISEASES
HAZARDS
ORGANS
RESPIRATORY SYSTEM
560300* - Chemicals Metabolism & Toxicology