Studies of the teratogenic potential of exposure of rats to 6000-MHz microwave radiation. II. Postnatal phychophysiologic evaluations

Journal Article · Wed Feb 01 04:00:00 EST 1984 · Radiat. Res.; (United States)

DOI:https://doi.org/10.2307/3576280· OSTI ID:5095393

Jensh, R P

Wistar rats (36) were exposed daily throughout pregnancy to a power density level of 35 mW/cm/sup 2/ of 6000-MHz microwave radiation (11), sham irradiated (10), or used as control animals (15). Litters were culled to a maximum of eight F/sub 1//sub a/ offspring/litter (total = 124) on Postnatal Day 1 and subjected to a series of reflex tests beginning Day 3. Mothers were rebred 10 days after weaning. Teratologic evaluations were completed on 263 F/sub 1//sub b/ offspring. Weekly weights were recorded for 298 F/sub 1//sub a/ offspring. At 60 days, behavioral testing was initiated on 121 offspring. At 90 days, offspring were bred within/across groups. Teratologic evaluations were completed on 659 F/sub 2/ term fetuses. Organ weight analyses were completed on 17 mothers and 181 F/sub 1//sub a/ adult offspring, and blood analyses on 21 mothers and 131 offspring. Sex differences within groups were observed in four behavioral tests and in blood data. Significant differences between groups were observed for: F/sub 1//sub b/ term fetal weight; F/sub 1//sub a/ eye opening, postnatal growth to the fifth week, water T-maze and open field test results; and several organ/body weight ratios. These results indicate that exposure to 6000-MHz radiation at this power density level may result in subtle long-term neurophysiologic alterations not detectable at term using conventional morphologic teratologic procedures.

• Research Organization: Jefferson Medical Coll., Philadelphia, PA
• OSTI ID: 5095393
• Journal Information: Radiat. Res.; (United States), Journal Name: Radiat. Res.; (United States) Vol. 97:2; ISSN RAREA
• Country of Publication: United States
• Language: English

Related Subjects

560152 -- Radiation Effects on Animals-- Animals
560400* -- Other Environmental Pollutant Effects
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ANIMAL GROWTH
ANIMALS
BEHAVIOR
BIOLOGICAL EFFECTS
DATA
ELECTROMAGNETIC RADIATION
EXPERIMENTAL DATA
FETUSES
FREQUENCY RANGE
GHZ RANGE
GHZ RANGE 01-100
GROWTH
INFORMATION
LITTER SIZE
MAMMALS
MICROWAVE RADIATION
NUMERICAL DATA
PREGNANCY
PRENATAL EXPOSURE
RADIATIONS
RATS
RODENTS
TERATOGENESIS
VERTEBRATES