Skip to main content
OSTI.GOVU.S. Department of Energy Office of Scientific and Technical Information
U.S. Department of Energy
Office of Scientific and Technical Information
 

Use of technetium-99m methylene diphosphonate and gallium-67 citrate scans after intraarticular injection of Staphylococcus aureus into knee joints of rabbits with chronic antigen-induced arthritis

Journal Article · · J. Infect. Dis.; (United States)
; ; ; ; ;

Numerous clinical studies have questioned the ability of radionuclide scans to differentiate septic from aseptic joint inflammation. A clinical study may not be able to document an underlying disease process or duration of infection and, thus, may make conclusions about the accuracy of scan interpretations open to debate. In this study, the Dumonde-Glynn model of antigen-induced arthritis in rabbits was used as the experimental model to study technetium and gallium scans in Staphylococcus aureus infection of arthritic and normal joints. Gallium scans were negative in normal rabbits, usually negative in antigen-induced arthritis, but positive in septic arthritis. The bone scan was usually negative in early infection but positive in late septic arthritis, a finding reflecting greater penetration of bacteria into subchondral bone because of the underlying inflammatory process.

OSTI ID:
5095089
Journal Information:
J. Infect. Dis.; (United States), Journal Name: J. Infect. Dis.; (United States) Vol. 2; ISSN JIDIA
Country of Publication:
United States
Language:
English

Similar Records

Technetium phosphate bone scan in the diagnosis of septic arthritis in childhood
Journal Article · Fri Sep 01 00:00:00 EDT 1989 · Journal of Pediatric Orthopedics; (USA) · OSTI ID:5226960
( sup 99m Tc)diphosphonate uptake and hemodynamics in arthritis of the immature dog knee
Journal Article · Thu Feb 28 23:00:00 EST 1991 · Journal of Orthopaedic Research; (USA) · OSTI ID:5893447
Septic arthritis of a lumbar facet joint: Detection with bone SPECT imaging
Journal Article · Tue Aug 01 00:00:00 EDT 1989 · Journal of Nuclear Medicine; (USA) · OSTI ID:5477249

Related Subjects

550601* -- Medicine-- Unsealed Radionuclides in Diagnostics
62 RADIOLOGY AND NUCLEAR MEDICINE
ACCURACY
ANIMALS
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BODY
BONE JOINTS
COUNTING TECHNIQUES
DAYS LIVING RADIOISOTOPES
DIAGNOSIS
DISEASES
ELECTRON CAPTURE RADIOISOTOPES
GALLIUM 67
GALLIUM ISOTOPES
HOURS LIVING RADIOISOTOPES
INFLAMMATION
INTERMEDIATE MASS NUCLEI
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
MAMMALS
NUCLEI
ODD-EVEN NUCLEI
ORGANS
PATHOLOGICAL CHANGES
RABBITS
RADIOISOTOPE SCANNING
RADIOISOTOPES
RHEUMATIC DISEASES
SKELETAL DISEASES
SKELETON
SYMPTOMS
TECHNETIUM 99
TECHNETIUM ISOTOPES
VERTEBRATES
YEARS LIVING RADIOISOTOPES