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Title: Early diagnosis of acute postoperative renal transplant rejection by indium-111-labeled platelet scintigraphy

Abstract

A prospective evaluation of /sup 111/In-labeled platelet scintigraphy (IPS) for the early diagnosis of acute postoperative renal transplant rejection (TR) was undertaken. The results of IPS were compared with in vitro biochemical tests, the clinical finding of graft tenderness, and combined (/sup 99m/Tc)DTPA and (/sup 131/I)orthoiodohippurate scintigraphy. With a sensitivity of 0.93 and a specificity of 0.95, IPS provided otherwise unavailable diagnostic information. Furthermore, postoperative IPS was a good predictor of long-term allograft survival.

Authors:
; ; ; ; ; ; ; ; ;
Publication Date:
Research Org.:
Medical College of Wisconsin, Milwaukee
OSTI Identifier:
5094896
Resource Type:
Journal Article
Resource Relation:
Journal Name: J. Nucl. Med.; (United States); Journal Volume: 8
Country of Publication:
United States
Language:
English
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; BLOOD PLATELETS; SCINTISCANNING; GRAFT-HOST REACTION; DIAGNOSIS; KIDNEYS; INDIUM 111; IODINE 131; PATIENTS; TECHNETIUM 99; TRANSPLANTS; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; BIOLOGICAL MATERIALS; BLOOD; BLOOD CELLS; BODY; BODY FLUIDS; COUNTING TECHNIQUES; DAYS LIVING RADIOISOTOPES; DIAGNOSTIC TECHNIQUES; ELECTRON CAPTURE RADIOISOTOPES; HOURS LIVING RADIOISOTOPES; INDIUM ISOTOPES; INTERMEDIATE MASS NUCLEI; IODINE ISOTOPES; ISOMERIC TRANSITION ISOTOPES; ISOTOPES; MATERIALS; MINUTES LIVING RADIOISOTOPES; NUCLEI; ODD-EVEN NUCLEI; ORGANS; RADIOISOTOPE SCANNING; RADIOISOTOPES; TECHNETIUM ISOTOPES; YEARS LIVING RADIOISOTOPES; 550601* - Medicine- Unsealed Radionuclides in Diagnostics

Citation Formats

Tisdale, P.L., Collier, B.D., Kauffman, H.M., Adams, M.B., Isitman, A.T., Hellman, R.S., Hoffmann, R.G., Rao, S.A., Joestgen, T., and Krohn, L. Early diagnosis of acute postoperative renal transplant rejection by indium-111-labeled platelet scintigraphy. United States: N. p., 1986. Web.
Tisdale, P.L., Collier, B.D., Kauffman, H.M., Adams, M.B., Isitman, A.T., Hellman, R.S., Hoffmann, R.G., Rao, S.A., Joestgen, T., & Krohn, L. Early diagnosis of acute postoperative renal transplant rejection by indium-111-labeled platelet scintigraphy. United States.
Tisdale, P.L., Collier, B.D., Kauffman, H.M., Adams, M.B., Isitman, A.T., Hellman, R.S., Hoffmann, R.G., Rao, S.A., Joestgen, T., and Krohn, L. Fri . "Early diagnosis of acute postoperative renal transplant rejection by indium-111-labeled platelet scintigraphy". United States. doi:.
@article{osti_5094896,
title = {Early diagnosis of acute postoperative renal transplant rejection by indium-111-labeled platelet scintigraphy},
author = {Tisdale, P.L. and Collier, B.D. and Kauffman, H.M. and Adams, M.B. and Isitman, A.T. and Hellman, R.S. and Hoffmann, R.G. and Rao, S.A. and Joestgen, T. and Krohn, L.},
abstractNote = {A prospective evaluation of /sup 111/In-labeled platelet scintigraphy (IPS) for the early diagnosis of acute postoperative renal transplant rejection (TR) was undertaken. The results of IPS were compared with in vitro biochemical tests, the clinical finding of graft tenderness, and combined (/sup 99m/Tc)DTPA and (/sup 131/I)orthoiodohippurate scintigraphy. With a sensitivity of 0.93 and a specificity of 0.95, IPS provided otherwise unavailable diagnostic information. Furthermore, postoperative IPS was a good predictor of long-term allograft survival.},
doi = {},
journal = {J. Nucl. Med.; (United States)},
number = ,
volume = 8,
place = {United States},
year = {Fri Aug 01 00:00:00 EDT 1986},
month = {Fri Aug 01 00:00:00 EDT 1986}
}