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Effects of selenium, cadmium, mercury, tellurium, arsenic, silver and cobalt on white muscle disease in lambs and effect of dietary forms of arsenic on its accumulation in tissues

Journal Article · · Nutr. Rep. Int.; (United States)
OSTI ID:5090538
; ; ;
The effects of feeding low selenium diets containing additions of cadmium (1 ppm), mercury (0.5 ppm), tellurium (2 ppm), arsenic (1 and 5 ppm), silver (50 ppm), or cobalt (25 ppm) to pregnant ewes on the development of white muscle disease (WMD) in their lambs were investigated. Some ewes were injected with selenium to serve as positive controls. The inclusion of cadmium, mercury, tellurium, arsenic, silver or cobalt in the diet had no significant influence on the incidence of WMD. In addition to histopathological studies, the effects of these metals on plasma levels of glutamicoxalacetic transaminase, creatine phosphokinase, and lactic dehydrogenase were used to evaluate WMD. Arsenic accumulated in tissues of lambs from ewes fed this element as sodium arsenate but this element was present in tissues of lambs from ewes fed arsenic as arsenic trioxide at levels similar to tissues from control lambs.
Research Organization:
Oregon State Univ., Corvallis
OSTI ID:
5090538
Journal Information:
Nutr. Rep. Int.; (United States), Journal Name: Nutr. Rep. Int.; (United States) Vol. 14:1; ISSN NURIB
Country of Publication:
United States
Language:
English

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Related Subjects

560305* -- Chemicals Metabolism & Toxicology-- Vertebrates-- (-1987)
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
AMINOTRANSFERASES
ANIMALS
ARSENIC
BIOLOGICAL ACCUMULATION
BIOLOGICAL EFFECTS
CADMIUM
COBALT
DATA
DIET
DISEASES
DOMESTIC ANIMALS
ELEMENTS
ENZYME ACTIVITY
ENZYMES
EXPERIMENTAL DATA
INFORMATION
MAMMALS
MERCURY
METALS
NITROGEN TRANSFERASES
NUMERICAL DATA
OXIDOREDUCTASES
PHOSPHORUS-GROUP TRANSFERASES
PHOSPHOTRANSFERASES
RUMINANTS
SELENIUM
SEMIMETALS
SHEEP
SILVER
TELLURIUM
TRANSFERASES
TRANSITION ELEMENTS
VERTEBRATES