Inducement of enlarged hearts and muscular dystrophy in turkey poults with dietary silver

Journal Article · Tue Jan 01 04:00:00 EST 1974 · Poult. Sci.; (United States)

DOI:https://doi.org/10.3382/ps.0530057· OSTI ID:5090418

Jensen, L S; Peterson, R P; Falen, L

Five experiments were conducted to determine the effect of adding silver acetate or nitrate to practical diets on growth of Large White turkey poults and incidence of pathological signs. The highest level of silver (900 p.p.m.) depressed growth rate, reduced packed cell volume, slightly reduced hemoglobin level and caused cardiac enlargement. The high silver level also induced a varying incidence of degeneration of the gizzard musculature which was completely prevented by adding 1 p.p.m. selenium or partially by adding 50 I.U. vitamin E/kg. diet. The anemia was of the microcytic, hyperchromic type and was not prevented by selenium or vitamin E. A high percentage of the enlarged hearts had a rounded apex similar to that observed in rough heart disease in turkeys. Feeding different basal diets containing silver showed that one having 10% distiller's dried solubles prevented the enlarged hearts. Copper at 50 p.p.m. completely reversed the effects of silver on growth rate, blood and cardiac tissue but 5 p.p.m. was inadequate. The results show that a high level of silver induced both a copper and selenium deficiency when added to practical diets for turkey poults.

• Research Organization: Washington State Univ., Pullman
• OSTI ID: 5090418
• Journal Information: Poult. Sci.; (United States), Journal Name: Poult. Sci.; (United States) Vol. 53:1; ISSN POSCA
• Country of Publication: United States
• Language: English

Related Subjects

560305* -- Chemicals Metabolism & Toxicology-- Vertebrates-- (-1987)
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ANIMALS
BIOLOGICAL EFFECTS
BIRDS
BODY
CARDIOVASCULAR SYSTEM
CENTRAL NERVOUS SYSTEM
COPPER
DATA
ELEMENTS
EXPERIMENTAL DATA
HEART
INFORMATION
METALS
MUSCLES
NERVOUS SYSTEM
NUMERICAL DATA
NUTRITIONAL DEFICIENCY
ORGANS
SELENIUM
SEMIMETALS
SILVER
TRANSITION ELEMENTS
VERTEBRATES
VITAMIN E
VITAMINS