Mortality of lead smelter workers
To examine patterns of death in lead smelter workers, a retrospective analysis of mortality was conducted in a cohort of 1,987 males employed between 1940 and 1965 at a primary lead smelter in Idaho. Overall mortality was similar to that of the United States white male population (standardized mortality ratio (SMR) = 98). Excess mortality, however, was found from chronic renal disease (SMR = 192; confidence interval (CI) = 88-364), and the risk of death from renal disease increased with increasing duration of employment, such that after 20 years employment, the standardized mortality ratio reached 392 (CI = 107-1,004). Excess mortality was also noted for nonmalignant respiratory disease (SMR = 187, CI = 128-264). Eight of 32 deaths in this category were caused by silicosis; at least five workers who died of silicosis had been miners for a part of their lives. An additional 11 deaths resulted from tuberculosis (SMR = 139; CI = 69-249); in six of these cases, silicosis was a contributory cause of death. Cancer mortality was not increased overall (SMR = 95; CI = 78-114). An increase, however, was noted for deaths from kidney cancer (six cases; SMR = 204; CI = 75-444). Finally, excess mortality was noted for injuries (SMR = 138; CI = 104-179); 13 (23%) of the 56 deaths in this category were caused by mining injuries. The data from this study are consistent with previous reports of increased mortality from chronic renal disease in persons exposed occupationally to lead.
- Research Organization:
- National Institute for Occupational Safety and Health, Cincinnati, OH
- OSTI ID:
- 5090244
- Journal Information:
- Am. J. Epidemiol.; (United States), Vol. 4
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
59 BASIC BIOLOGICAL SCIENCES
LEAD
HEALTH HAZARDS
PERSONNEL
MORTALITY
SMELTERS
AIR POLLUTION
CARDIOVASCULAR DISEASES
EPIDEMIOLOGY
IDAHO
INJURIES
MINING
NEOPLASMS
OCCUPATIONAL DISEASES
RESPIRATORY SYSTEM DISEASES
RISK ASSESSMENT
UROGENITAL SYSTEM DISEASES
DISEASES
ELEMENTS
FEDERAL REGION X
HAZARDS
METALS
NORTH AMERICA
POLLUTION
USA
560306* - Chemicals Metabolism & Toxicology- Man- (-1987)
550900 - Pathology