Laser-excited fluorescence, photoacoustic, and photoionization detection of polyaromatic hydrocarbons and drugs

Conference · Mon Mar 01 04:00:00 EST 1982 · Am. Soc. Test. Mater., Spec. Tech. Publ.; (United States)

OSTI ID:5081674

Winefordner, J D; Voigtman, E

Methods of enhancing the spectral selectivity for identification and quantitation of molecules in complex systems, such as polynuclear aromatic hydrocarbons (PAHs) in environmental samples or drugs in biological materials, are mentioned. The major emphasis concerns the description of the instrumentation and analytical figures of merit for a three-mode cuvette and a three-mode flow cell detection system based upon fluorescence, photoacoustic, and photoionization detection. The instrumental system consisting of a laser (nitrogen (N/sub 2/) laser or N/sub 2/-dye laser), the cell assembly, and the detection system is briefly described for all three modes for each type of cell. Limits of detection for the three modes are given and compared forseveral selected molecules. A model five-compound mixture is separated by high-performance liquid chromatography (HPLC) and detected with the three-mode flow detector. The mechanism of the photoionization detection is briefly discussed.

• Research Organization: Department of Chemistry, University of Florida, Gainesville, FL
• OSTI ID: 5081674
• Report Number(s): CONF-8203163-
• Conference Information: Journal Name: Am. Soc. Test. Mater., Spec. Tech. Publ.; (United States) Journal Volume: STP822
• Country of Publication: United States
• Language: English

Related Subjects

500200* -- Environment
Atmospheric-- Chemicals Monitoring & Transport-- (-1989)
54 ENVIRONMENTAL SCIENCES
AROMATICS
BIOLOGICAL MATERIALS
CHROMATOGRAPHY
DETECTION
DRUGS
ELEMENTS
EMISSION SPECTROSCOPY
FLUORESCENCE SPECTROSCOPY
HYDROCARBONS
IONIZATION
LASER SPECTROSCOPY
LASERS
LIQUID COLUMN CHROMATOGRAPHY
MATERIALS
NITROGEN
NONMETALS
ORGANIC COMPOUNDS
PHOTOACOUSTIC SPECTROSCOPY
PHOTOIONIZATION
POLYCYCLIC AROMATIC HYDROCARBONS
SEPARATION PROCESSES
SPECTROSCOPY