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Title: Acceleration of maximum likelihood reconstruction, using frequency amplification and attenuation compensation

Journal Article · · IEEE Transactions on Medical Imaging (Institute of Electrical and Electronics Engineers); (United States)
DOI:https://doi.org/10.1109/42.251114· OSTI ID:5079507
;  [1];  [2]
  1. Katholieke Univ. Leuven (Belgium). Dept. of Nuclear Medicine
  2. Katholieke Univ. Leuven (Belgium). Dept. of Electrical Engineering

Algorithms that calculate maximum likelihood (ML) and maximum a posteriori solutions using expectation-maximization have been successfully applied to SPECT and PET. These algorithms are appealing because of their solid theoretical basis and their guaranteed convergence. A major drawback is the slow convergence, which results in long processing times. This paper presents two new heuristic acceleration methods for maximum likelihood reconstruction of ECT images. The first method incorporates a frequency-dependent amplification in the calculations, to compensate for the low pass filtering of the back projection operation. In the second method, an amplification factor is incorporated that suppresses the effect of attenuation on the updating factors. Both methods are compared to the one-dimensional line search method proposed by Lewitt. All three methods accelerate the ML algorithm. On the test images, Lewitt's method produced the strongest acceleration of the three individual methods. However, the combination of the frequency amplification with the line search method results in a new algorithm with still better performance. Under certain conditions, an effective frequency amplification can be already achieved by skipping some of the calculations required for ML.

OSTI ID:
5079507
Journal Information:
IEEE Transactions on Medical Imaging (Institute of Electrical and Electronics Engineers); (United States), Vol. 12:4; ISSN 0278-0062
Country of Publication:
United States
Language:
English