Filtering of SPECT reconstructions made using Bellini's attenuation correction method; A comparison of three pre-reconstruction filters and a post-reconstruction Wiener filter

Journal Article · Mon Apr 01 04:00:00 EST 1991 · IEEE Transactions on Nuclear Science (Institute of Electrical and Electronics Engineers); (United States)

DOI:https://doi.org/10.1109/23.289372· OSTI ID:5076219

Glick, S J; Penney, B C; King, M A ^[1]

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1. Dept. of Nuclear Medicine, Univ. of Massachusetts Medical Center, Worcester, MA (US)

This paper evaluates a three-dimensional (3D) Wiener filter which is used to restore SPECT reconstructions which were made using Bellini's method of attenuation correction. Its performance is compared to that of several pre-reconstruction filers: the one-dimensional (1D) Butterworth, the two-dimensional (2D) Butterworth, and a 2D Wiener filer. A simulation study is used to compare the four filtering methods. An approximation to a clinical liver spleen study was used as the source distribution and algorithm which accounts for the depth and distance dependent blurring in SPECT was used to compute noise free projections. To study the effect of filtering method on tumor detection accuracy, a 2 cm diameter, cool spherical tumor (40% contrast) was placed at a known, but random, location with the liver. Projection sets for ten tumor locations were computed and five noise realizations of each set were obtained by introducing Poisson noise. The simulated projections were either: filtered with the 1D or 2D Butterworth or the 2D Wiener and then reconstructed using Bellini's intrinsic attenuation correction, or reconstructed first, then filtered with the 3D Wiener. The criteria used for comparison were: normalized mean square error (NMSE), cold spot contrast, and accuracy of tumor detection with an automated numerical method. Results indicate that restorations obtained with 3D Wiener filtering yielded significantly higher lesion contrast and lower NMSE values compared to the other methods of processing. The Wiener restoration filters and the 2D Butterworth all provided similar measures of detectability, which were noticeably higher than that obtained with 1D Butterworth smoothing.

• OSTI ID: 5076219
• Journal Information: IEEE Transactions on Nuclear Science (Institute of Electrical and Electronics Engineers); (United States), Journal Name: IEEE Transactions on Nuclear Science (Institute of Electrical and Electronics Engineers); (United States) Vol. 38:2; ISSN 0018-9499; ISSN IETNA
• Country of Publication: United States
• Language: English

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550602* -- Medicine-- External Radiation in Diagnostics-- (1980-)
62 RADIOLOGY AND NUCLEAR MEDICINE
ALGORITHMS
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COMPARATIVE EVALUATIONS
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DIAGNOSTIC TECHNIQUES
DIGESTIVE SYSTEM
DISEASES
EMISSION COMPUTED TOMOGRAPHY
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