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Title: Pyrophosphate-based method and apparatus for sequencing nucleic acids

Patent ·
OSTI ID:5060133

This patent describes a method for determining the nucleic acid sequence in a template nucleic acid polymer. It comprises: introducing the template nucleic acid polymer into a polymerization environment; successively providing to the polymerization environment a series of feedstocks; separately recovering each of the feedstocks from the polymerization environment; and measuring the amount of inorganic pyrophosphate.

Assignee:
NOV; NOV-91-015231; EDB-91-154753
Patent Number(s):
US 4971903; A
Application Number:
PPN: US 7-173-433
OSTI ID:
5060133
Resource Relation:
Patent File Date: 25 Mar 1988
Country of Publication:
United States
Language:
English

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Related Subjects

59 BASIC BIOLOGICAL SCIENCES
47 OTHER INSTRUMENTATION
MEASURING INSTRUMENTS
ORGANIC POLYMERS
DNA SEQUENCING
DNA
NUCLEOTIDES
PHOSPHATES
POLYMERIZATION
SYNTHESIS
CHEMICAL REACTIONS
NUCLEIC ACIDS
ORGANIC COMPOUNDS
OXYGEN COMPOUNDS
PHOSPHORUS COMPOUNDS
POLYMERS
STRUCTURAL CHEMICAL ANALYSIS
550200* - Biochemistry
440800 - Miscellaneous Instrumentation- (1990-)