Development and application of photosensitive device systems to studies of biological and organic materials
This report describes the progress of the second year of a 3-year DOE grant DE-FG-02-87ER60522 for the fiscal period 1/1/91 to 12/31/91 as of July 1991. The overall goals of the grant are to develop novel instrumentation and techniques for the performance of biological and materials research and to apply the new developments to basic biological and materials research problems. Since the last progress report, dated July 1990, there has been significant progress on most of the originally proposed instrumentation and applications research. The overall research goals proposed for the next year have not changed from those originally listed. A prototype large area CCD x-ray detector was assembled and evaluated at the CHESS synchrotron facility. Fiber optic CCD coupling methods have been developed and are being applied to in-house detector needs. Novel detector control and calibration software was developed and refined. Novel high pressure x-ray diffraction and dilatometric apparatus were designed and built, and are being applied to the study of membrane-lipid phase behavior. A time-resolved x-ray diffraction study of lipid phase transitions was used to demonstrate that conventual calorimetry does not accurately determine the phase transition parameters. The elastic properties of amphiphilic layers were studied both theoretically and experimentally. A re-entrant hexagonal-lamellar-hexagonal lipid phase transition was discovered and studied. Each of these accomplishments are detailed.
- Research Organization:
- Princeton Univ., NJ (United States). Joseph Henry Labs.
- Sponsoring Organization:
- USDOE; USDOE, Washington, DC (United States)
- DOE Contract Number:
- FG02-87ER60522
- OSTI ID:
- 5051836
- Report Number(s):
- DOE/ER/60522-5; ON: DE92002722
- Country of Publication:
- United States
- Language:
- English
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Development and application of photosensitive device systems to studies of biological and organic materials
Development and application of photosensitive device systems to studies of biological and organic materials. Third year progress report, January 1, 1992--December 31, 1992
Related Subjects
46 INSTRUMENTATION RELATED TO NUCLEAR SCIENCE AND TECHNOLOGY
BIOLOGICAL MATERIALS
X-RAY DIFFRACTION
ORGANIC COMPOUNDS
CALIBRATION
CHARGE-COUPLED DEVICES
COMPUTER ARCHITECTURE
ELASTICITY
FIBER OPTICS
LIPIDS
PROGRESS REPORT
X-RAY DETECTION
COHERENT SCATTERING
DETECTION
DIFFRACTION
DOCUMENT TYPES
MATERIALS
MECHANICAL PROPERTIES
RADIATION DETECTION
SCATTERING
SEMICONDUCTOR DEVICES
TENSILE PROPERTIES
360602* - Other Materials- Structure & Phase Studies
440100 - Radiation Instrumentation