Soft-x-ray experiment revisited: a theoretical analysis
Conference
·
OSTI ID:5049042
The generalized formulation of the Theory of Dual Radiation Action (TDRA) deals quantitatively with the process of sublesion-lesion production in sensitive sites irradiated with uniform fields of ionizing radiation. In this paper modifications of this formalism necessary to treat the case of attenuated fields of radiations are described. As an application, recent survival data obtained with soft x-ray experiments are analyzed. It is shown that: (1) given a linear-quadratic dose-effect relation with constant ..beta..; (2) the function ..gamma..(x) can be obtained with the aid of Monte-Carlo generated proximity functions; and (3) this ..gamma..(x) may be successfully utilized to account for survival results obtained, with the same cell line, using ..cap alpha.. particles.
- Research Organization:
- Los Alamos National Lab., NM (USA); Columbia Univ., New York (USA). Radiological Research Lab.
- DOE Contract Number:
- W-7405-ENG-36
- OSTI ID:
- 5049042
- Report Number(s):
- LA-UR-82-2460; CONF-820931-2; ON: DE82021895
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
560121* -- Radiation Effects on Cells-- External Source-- (-1987)
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ANIMAL CELLS
BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
CELL CULTURES
DOSE-RESPONSE RELATIONSHIPS
ELECTROMAGNETIC RADIATION
ENERGY TRANSFER
HYPOTHESIS
IONIZING RADIATIONS
IRRADIATION
MONTE CARLO METHOD
NONUNIFORM IRRADIATION
RADIATION EFFECTS
RADIATIONS
SOFT X RADIATION
SURVIVAL TIME
X RADIATION
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ANIMAL CELLS
BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
CELL CULTURES
DOSE-RESPONSE RELATIONSHIPS
ELECTROMAGNETIC RADIATION
ENERGY TRANSFER
HYPOTHESIS
IONIZING RADIATIONS
IRRADIATION
MONTE CARLO METHOD
NONUNIFORM IRRADIATION
RADIATION EFFECTS
RADIATIONS
SOFT X RADIATION
SURVIVAL TIME
X RADIATION