Synthesis of radiopharmaceuticals containing short-lived radionuclides. Progress report, March 1, 1985-February 26, 1986
Technical Report
·
OSTI ID:5046436
Methods for the rapid introduction of short-lived radionuclides into agents for use in diagnostic nuclear medicine are reported. Methods to synthesize radioiodinated fatty acids, lipids, and amphetamine derivatives are described. New routes for the introduction of bromine-77, chlorine-34m, and carbon-11 into agents of interest are elaborated. 46 refs.
- Research Organization:
- Tennessee Univ., Knoxville (USA). Dept. of Chemistry
- DOE Contract Number:
- AS05-80EV10363
- OSTI ID:
- 5046436
- Report Number(s):
- DOE/EV/10363-7; ON: DE86001891
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
38 RADIATION CHEMISTRY, RADIOCHEMISTRY, AND NUCLEAR CHEMISTRY
400702* -- Radiochemistry & Nuclear Chemistry-- Properties of Radioactive Materials
550601 -- Medicine-- Unsealed Radionuclides in Diagnostics
62 RADIOLOGY AND NUCLEAR MEDICINE
AMPHETAMINES
ANALEPTICS
AROMATICS
AUTONOMIC NERVOUS SYSTEM AGENTS
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BETA-PLUS DECAY RADIOISOTOPES
BROMINE 82
BROMINE ISOTOPES
CARBOXYLIC ACIDS
CELL CONSTITUENTS
CENTRAL NERVOUS SYSTEM AGENTS
CHEMICAL PREPARATION
CHEMISTRY
CHOLESTEROL
DAYS LIVING RADIOISOTOPES
DRUGS
ELECTRON CAPTURE RADIOISOTOPES
EVEN-ODD NUCLEI
HOURS LIVING RADIOISOTOPES
HYDROXY COMPOUNDS
INTERMEDIATE MASS NUCLEI
IODINE 123
IODINE ISOTOPES
ISOTOPES
LABELLED COMPOUNDS
LABELLING
LIGHT NUCLEI
LIPOSOMES
MINUTES LIVING RADIOISOTOPES
MONOCARBOXYLIC ACIDS
NITROGEN 15
NITROGEN ISOTOPES
NUCLEI
ODD-EVEN NUCLEI
ODD-ODD NUCLEI
ORGANIC ACIDS
ORGANIC BORON COMPOUNDS
ORGANIC COMPOUNDS
ORGANOIDS
OXYGEN 15
OXYGEN ISOTOPES
RADIOCHEMISTRY
RADIOISOTOPES
RADIOPHARMACEUTICALS
STABLE ISOTOPES
STEROIDS
STEROLS
SYMPATHOMIMETICS
SYNTHESIS
400702* -- Radiochemistry & Nuclear Chemistry-- Properties of Radioactive Materials
550601 -- Medicine-- Unsealed Radionuclides in Diagnostics
62 RADIOLOGY AND NUCLEAR MEDICINE
AMPHETAMINES
ANALEPTICS
AROMATICS
AUTONOMIC NERVOUS SYSTEM AGENTS
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BETA-PLUS DECAY RADIOISOTOPES
BROMINE 82
BROMINE ISOTOPES
CARBOXYLIC ACIDS
CELL CONSTITUENTS
CENTRAL NERVOUS SYSTEM AGENTS
CHEMICAL PREPARATION
CHEMISTRY
CHOLESTEROL
DAYS LIVING RADIOISOTOPES
DRUGS
ELECTRON CAPTURE RADIOISOTOPES
EVEN-ODD NUCLEI
HOURS LIVING RADIOISOTOPES
HYDROXY COMPOUNDS
INTERMEDIATE MASS NUCLEI
IODINE 123
IODINE ISOTOPES
ISOTOPES
LABELLED COMPOUNDS
LABELLING
LIGHT NUCLEI
LIPOSOMES
MINUTES LIVING RADIOISOTOPES
MONOCARBOXYLIC ACIDS
NITROGEN 15
NITROGEN ISOTOPES
NUCLEI
ODD-EVEN NUCLEI
ODD-ODD NUCLEI
ORGANIC ACIDS
ORGANIC BORON COMPOUNDS
ORGANIC COMPOUNDS
ORGANOIDS
OXYGEN 15
OXYGEN ISOTOPES
RADIOCHEMISTRY
RADIOISOTOPES
RADIOPHARMACEUTICALS
STABLE ISOTOPES
STEROIDS
STEROLS
SYMPATHOMIMETICS
SYNTHESIS