Neurogenesis in the brain auditory pathway of a marsupial, the northern native cat (Dasyurus hallucatus)

Journal Article · Mon Jul 08 04:00:00 EDT 1991 · Journal of Comparative Neurology; (United States)

DOI:https://doi.org/10.1002/cne.903090206· OSTI ID:5045243

Aitkin, L; Nelson, J; Farrington, M; Swann, S ^[1]

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1. Department of Physiology, Monash University, Melbourne (Australia)

Neurogenesis in the auditory pathway of the marsupial Dasyurus hallucatus was studied. Intraperitoneal injections of tritiated thymidine (20-40 microCi) were made into pouch-young varying from 1 to 56 days pouch-life. Animals were killed as adults and brain sections were prepared for autoradiography and counterstained with a Nissl stain. Neurons in the ventral cochlear nucleus were generated prior to 3 days pouch-life, in the superior olive at 5-7 days, and in the dorsal cochlear nucleus over a prolonged period. Inferior collicular neurogenesis lagged behind that in the medial geniculate, the latter taking place between days 3 and 9 and the former between days 7 and 22. Neurogenesis began in the auditory cortex on day 9 and was completed by about day 42. Thus neurogenesis was complete in the medullary auditory nuclei before that in the midbrain commenced, and in the medial geniculate before that in the auditory cortex commenced. The time course of neurogenesis in the auditory pathway of the native cat was very similar to that in another marsupial, the brushtail possum. For both, neurogenesis occurred earlier than in eutherian mammals of a similar size but was more protracted.

• OSTI ID: 5045243
• Journal Information: Journal of Comparative Neurology; (United States), Journal Name: Journal of Comparative Neurology; (United States) Vol. 309:2; ISSN 0021-9967; ISSN JCNEA
• Country of Publication: United States
• Language: English

Related Subjects

550201* -- Biochemistry-- Tracer Techniques
59 BASIC BIOLOGICAL SCIENCES
ANIMAL CELLS
ANIMALS
AUDITORY ORGANS
AUTORADIOGRAPHY
AZINES
BIOLOGICAL PATHWAYS
BODY
BRAIN
CENTRAL NERVOUS SYSTEM
DNA REPLICATION
HETEROCYCLIC COMPOUNDS
HYDROGEN COMPOUNDS
MAMMALS
MARSUPIALS
NERVE CELLS
NERVOUS SYSTEM
NUCLEIC ACID REPLICATION
NUCLEOSIDES
NUCLEOTIDES
ONTOGENESIS
ORGANIC COMPOUNDS
ORGANIC NITROGEN COMPOUNDS
ORGANS
PYRIMIDINES
RIBOSIDES
SENSE ORGANS
SOMATIC CELLS
THYMIDINE
TRITIUM COMPOUNDS
VERTEBRATES