Observations on polycythemia vera turning into acute or chronic granulocytic leukemia during treatment with radioactive phosphorus /sup 32/P

Journal Article · Wed Jan 01 00:00:00 EST 1975 · Pol. Med. Sci. Hist. Bull. (Engl. Transl.); (United States)

OSTI ID:5038940

Krasnik, W

In a group of 172 cases of polycythemia vera treated with radioactive phosphorus acute granulocytic leukemia developed in 3 and chronic granulocytic leukemia in 6 cases. The author believes that development of acute granulocytic leukemia during this treatment may be considered with some probability as a result of the leukemia-inducing action of ionizing radiation. Transition of polycythemia vera into chronic granulocytic leukemia seems to be a natural outcome of this complex myeloproliferative syndrome in patients with survival prolonged by treatment with /sup 32/P.

• Research Organization: Poznan Hematological Clinic, Poland
• OSTI ID: 5038940
• Journal Information: Pol. Med. Sci. Hist. Bull. (Engl. Transl.); (United States), Vol. 15:4; Other Information: Translated from Pol. Tyg. Lek.; 30: No. 6, 233-236(1975)
• Country of Publication: United States
• Language: English

Related Subjects

63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
LEUKEMIA
RADIOINDUCTION
PATIENTS
BIOLOGICAL RADIATION EFFECTS
PHOSPHORUS 32
LEUKEMOGENESIS
RADIOTHERAPY
SIDE EFFECTS
POLYCYTHEMIA
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BIOLOGICAL EFFECTS
CARCINOGENESIS
DAYS LIVING RADIOISOTOPES
DISEASES
HEMIC DISEASES
ISOTOPES
LIGHT NUCLEI
MEDICINE
NEOPLASMS
NUCLEAR MEDICINE
NUCLEI
ODD-ODD NUCLEI
PATHOGENESIS
PHOSPHORUS ISOTOPES
RADIATION EFFECTS
RADIOISOTOPES
RADIOLOGY
THERAPY
560151* - Radiation Effects on Animals- Man