Ga-67 uptake in the lung in sarcoidosis
Images were obtained with Ga-67 and bronchopulmonary lavage performed in 21 patients with sarcoidosis (31 studies). The Ga-67 index, a semiquantitative criterion, was compared to a quantitative computer index based on lung:liver activity ratios; accuracy in predicting active alveolitis (defined by lavage lymphocyte counts) was assessed and differences between 24- and 48-hour studies examined. Computer activity ratios correlated well with the Ga-67 index, which had a sensitivity of 64%, specificity of 71%, 82%, and 77%, respectively, for the computer scores. Scores at 24 and 48 hours were similar. These results suggest that (a) Ga-67 scanning is useful in staging activity in pulmonary sarcoidosis, (b) quantitative computer scores are accurate in predicting disease activity, and (c) scanning can be performed 24 or 48 hours after injection.
- Research Organization:
- Duke Univ. Medical Center, Durham, NC
- OSTI ID:
- 5022076
- Journal Information:
- Radiology; (United States), Vol. 150:2
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
LUNGS
SCINTISCANNING
RESPIRATORY SYSTEM DISEASES
DIAGNOSIS
GALLIUM 67
INFLAMMATION
LAVAGE
PATIENTS
BETA DECAY RADIOISOTOPES
BODY
COUNTING TECHNIQUES
DAYS LIVING RADIOISOTOPES
DIAGNOSTIC TECHNIQUES
DISEASES
ELECTRON CAPTURE RADIOISOTOPES
GALLIUM ISOTOPES
INTERMEDIATE MASS NUCLEI
ISOTOPES
NUCLEI
ODD-EVEN NUCLEI
ORGANS
PATHOLOGICAL CHANGES
RADIOISOTOPE SCANNING
RADIOISOTOPES
RESPIRATORY SYSTEM
SYMPTOMS
550601* - Medicine- Unsealed Radionuclides in Diagnostics