Metabolic changes in humans following total body irradiation. Report for February 1960-October 1961
These studies are designed to obtain new information about the metabolic effects of total body and partial body irradiation so as to have a better understanding of the acute and subacute effects of irradiation in the human. The initial studies are pointed toward the elucidation of biological indicators of radiation effects in humans. The major parameters being investigated at present are urinary amino aciduria and alterations in immunological patterns. Certain other parameters such as creatine and creatinine excretion and hematological effects are also being followed. The long-term program envisions carrying out the various observations at dose levels of 100 rad and gradually increasing the dose to 150, 200, 250 and 300 rad. Eventually doses up to 600 rad are anticipated. Also comparison of effects of radiomimetic drugs with total body radiation will be studied.
- Research Organization:
- Cincinnati Univ., OH (United States). Coll. of Medicine
- OSTI ID:
- 5012655
- Report Number(s):
- PB-94-127800/XAB; CNN: DA-49-146-XZ-029
- Country of Publication:
- United States
- Language:
- English
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63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
AMINO ACIDS
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BIOLOGICAL INDICATORS
BIOLOGICAL RADIATION EFFECTS
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IRRADIATION
METABOLISM
ORGANIC ACIDS
ORGANIC COMPOUNDS
PARTIAL BODY IRRADIATION
POPULATIONS
RADIATION EFFECTS
WHOLE-BODY IRRADIATION