Cholangiographic evaluation of bile duct carcinoma

Journal Article · Thu Dec 01 04:00:00 EST 1983 · AJR, Am. J. Roentgenol.; (United States)

DOI:https://doi.org/10.2214/ajr.141.6.1291· OSTI ID:5012615

Nichols, D A; MacCarty, R L; Gaffey, T A

Cholangiograms and clinical histories of 82 patients with biopsy-proved bile duct carcinoma were reviewed. The carcinomas were classified according to morphologic findings and clinical outcome. Ulcerative colitis and antecedent inflammatory disease of the biliary tree, particularly primary sclerosing cholangitis, seem to predispose to the development of bile duct carcinoma. Focal stenotic lesions were the most common morphologic type (62/82). Polypoid carcinomas and diffuse sclerosing carcinomas were less common and of about equal frequency. Prognosis was best for patients with polypoid carcinomas and worst for those with diffuse sclerosing carcinomas. In 69 cases (84%), the tumors involved the intrahepatic or proximal extrahepatic ducts, makin curative resection difficult or impossible. Patients with carcinomas limited to the more distal extrahepatic bile ducts had a longer average survival and a higher probability of surgical cure. Proper management of patients with bile duct carcinoma requires a complete and accurate cholangiographic evaluation of the morphology, location, and extent of the disease.

• Research Organization: Mayo Clinic, Rochester, MN
• OSTI ID: 5012615
• Journal Information: AJR, Am. J. Roentgenol.; (United States), Journal Name: AJR, Am. J. Roentgenol.; (United States) Vol. 141:6; ISSN AAJRD
• Country of Publication: United States
• Language: English

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59 BASIC BIOLOGICAL SCIENCES
62 RADIOLOGY AND NUCLEAR MEDICINE
BILIARY TRACT
BIOMEDICAL RADIOGRAPHY
CARCINOMAS
DIAGNOSTIC TECHNIQUES
DIGESTIVE SYSTEM
DISEASES
INFLAMMATION
MEDICINE
NEOPLASMS
NUCLEAR MEDICINE
PATHOLOGICAL CHANGES
PATHOLOGY
PATIENTS
RADIOLOGY
SYMPTOMS