Low-dose radiation: a cause of breast cancer
It is likely that the breast is the organ most sensitive to radiation carcinogenesis in postpubertal women. Studies of different exposed populations have yielded remarkably consistent results, in spite of wide differences in underlying breast cancer rates and conditions of exposure. Excess risk is approximately proportional to dose, and is relatively independent of ionization density and fractionization of dose. This implies that the risk associated with low-dose exposures to ionizing radiation can be estimated with some confidence from higher-dose data. Excess risk is heavily dependent on age at exposure but relatively independent of population differences in normal risk. The temporal patterns after exposure of both radiation-induced and naturally occurring breast cancer are similar, suggesting a strong influence of factors other than radiation on radiation-induced breast cancer. Uncertainties remain about risks from exposures before puberty and after menopause.
- OSTI ID:
- 5006311
- Journal Information:
- Cancer; (United States), Vol. 46:4; Conference: American Cancer Society national conference on breast cancer-1979, New York, NY, USA, 6 Sep 1979
- Country of Publication:
- United States
- Language:
- English
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62 RADIOLOGY AND NUCLEAR MEDICINE
CARCINOGENESIS
RISK ASSESSMENT
GAMMA RADIATION
COMPARATIVE EVALUATIONS
MAMMARY GLANDS
DELAYED RADIATION EFFECTS
NEOPLASMS
RADIOINDUCTION
NEUTRONS
X RADIATION
A-BOMB SURVIVORS
ACUTE IRRADIATION
AGE DEPENDENCE
CHRONIC IRRADIATION
DOSE-RESPONSE RELATIONSHIPS
FLUOROSCOPY
LOW DOSE IRRADIATION
WOMEN
ACUTE EXPOSURE
ANIMALS
BARYONS
BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
BIOMEDICAL RADIOGRAPHY
BODY
CHRONIC EXPOSURE
DIAGNOSTIC TECHNIQUES
DISEASES
ELECTROMAGNETIC RADIATION
ELEMENTARY PARTICLES
FEMALES
FERMIONS
GLANDS
HADRONS
IONIZING RADIATIONS
IRRADIATION
MAMMALS
MAN
MEDICINE
NUCLEAR MEDICINE
NUCLEONS
ORGANS
PATHOGENESIS
PRIMATES
RADIATION EFFECTS
RADIATIONS
RADIOLOGY
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