Hematological responses of sea bass Dicentrarchus labrax to sublethal nitrite exposures
Journal Article
·
· Trans. Am. Fish. Soc.; (United States)
Hemoglobin, methemoglobin, and blood nitrite concentrations were determined during and after 96-hour exposures of sea bass Dicentrarchus labrax to sublethal concentrations of nitrite in seawater at 26 C. As exposure time or exposure concentration increased, total and functional hemoglobin concentrations decreased in blood, while percent methemoglobin increased. The 96-hour median effective concentrations of nitrite in seawater (EC50, the concentration causing 50% reduction in blood) were 87.2 mg/liter for total hemoglobin (95% confidence limits, 64-118 mg/liter) and 62.4 mg/liter (45-87 mg/liter) for functional hemoglobin. Histochemical analysis of spleen tissues from fish exposed to 50 and 75 mg/liter NO/sub 2/-N, which reduced total hemoglobin to 17% and 49%, respectively, showed Fe/sup + + +/ originating from hemoglobin destruction and indicated hemolytic anemia caused by spleen marcophages. Nitrite concentrations in blood were lower than those in test water. Inhibition of nitrite uptake by chloride in seawater may protect sea bass against nitrite toxicity. 18 references, 3 figures, 1 table.
- Research Organization:
- National Council of Research (CNR), Lesina, Italy
- OSTI ID:
- 5001096
- Journal Information:
- Trans. Am. Fish. Soc.; (United States), Journal Name: Trans. Am. Fish. Soc.; (United States) Vol. 113:3; ISSN TAFSA
- Country of Publication:
- United States
- Language:
- English
Similar Records
Chemical residues and biochemical responses in wild and cultured European sea bass (Dicentrarchus labrax L.)
Nitrite-induced anemia in channel catfish, Ictalurus punctatus Rafinesque
Seawater inhibition of nitric toxicity to chinook salmon
Journal Article
·
Wed Feb 14 23:00:00 EST 2007
· Environmental Research
·
OSTI ID:20972065
Nitrite-induced anemia in channel catfish, Ictalurus punctatus Rafinesque
Journal Article
·
Tue Aug 01 00:00:00 EDT 1989
· Bulletin of Environmental Contamination and Toxicology; (USA)
·
OSTI ID:7244243
Seawater inhibition of nitric toxicity to chinook salmon
Journal Article
·
Fri Dec 31 23:00:00 EST 1976
· Trans. Am. Fish. Soc.; (United States)
·
OSTI ID:7106728
Related Subjects
560305* -- Chemicals Metabolism & Toxicology-- Vertebrates-- (-1987)
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ANIMALS
AQUATIC ORGANISMS
BIOLOGICAL EFFECTS
BLOOD CHEMISTRY
CARBOXYLIC ACIDS
FISHES
GLOBIN
HEMATOLOGY
HEMOGLOBIN
HETEROCYCLIC ACIDS
HETEROCYCLIC COMPOUNDS
HYDROGEN COMPOUNDS
MEDICINE
METHEMOGLOBIN
NITRITES
NITROGEN COMPOUNDS
ORGANIC ACIDS
ORGANIC COMPOUNDS
ORGANIC NITROGEN COMPOUNDS
OXYGEN COMPOUNDS
PIGMENTS
PORPHYRINS
PROTEINS
SEAWATER
TOXICITY
VERTEBRATES
WATER
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ANIMALS
AQUATIC ORGANISMS
BIOLOGICAL EFFECTS
BLOOD CHEMISTRY
CARBOXYLIC ACIDS
FISHES
GLOBIN
HEMATOLOGY
HEMOGLOBIN
HETEROCYCLIC ACIDS
HETEROCYCLIC COMPOUNDS
HYDROGEN COMPOUNDS
MEDICINE
METHEMOGLOBIN
NITRITES
NITROGEN COMPOUNDS
ORGANIC ACIDS
ORGANIC COMPOUNDS
ORGANIC NITROGEN COMPOUNDS
OXYGEN COMPOUNDS
PIGMENTS
PORPHYRINS
PROTEINS
SEAWATER
TOXICITY
VERTEBRATES
WATER