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1,1,1-Trimethylhydrazinium iodide: A novel, highly reactive reagent for aromatic amination via vicarious nucleophilic substitution of hydrogen

Journal Article · · Journal of Organic Chemistry
DOI:https://doi.org/10.1021/jo952257z· OSTI ID:494236
; ;  [1]
  1. Lawrence Livermore National Lab., CA (United States)

1,1,1-Trimethylhydrazinium iodide, TMHI, has been shown to be a novel vicarious nucleophilic substitution aminating reagent. It can be used to obtain isomers not produced by reaction with other nucleophilic aminating reagents. It is easily prepared from 1,1-dimethylhydrazine, or directly from hydrazine. Further studies on the use of TMHI and related quaternary hydrazines as nucleophlic aminating reagents are in progress. 1 tab.

DOE Contract Number:
W-7405-ENG-48
OSTI ID:
494236
Journal Information:
Journal of Organic Chemistry, Journal Name: Journal of Organic Chemistry Journal Issue: 9 Vol. 61; ISSN 0022-3263; ISSN JOCEAH
Country of Publication:
United States
Language:
English