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Simultaneous determination of arsenic, manganese, and selenium in human serum by neutron activation analysis

Technical Report ·
OSTI ID:4936684
A procedure for the simultaneous determination of arsenic, manganese, and selenium in human serum is described, and its performance characteristics are evaluated with particular reference to manganese. Blank values depend critically on irradiation containers, and only one type of polyethylene ampoule gave a sufficiently low limit of detection. Other suspected sources of random and systematic errors are investigated; they did not, however, jeopardize precision or accuracy of analytical results, Careful studies of the sampling techniques with actual as well as simulated serum revealed considerable contamination with arsenic and managainst contamination is described and is shown to yield meaningful results for normal, human serum. Results tend to agree with the lowest values reported in the literature, and the analytical precision is sufficient for determination of the standard deviation of the distribution of all three elements in human serum. (auth)
Research Organization:
Danish Atomic Energy Commission, Risoe. Research Establishment
Sponsoring Organization:
Sponsor not identified
NSA Number:
NSA-29-015234
OSTI ID:
4936684
Report Number(s):
RISO--271; CONF-710623--3
Country of Publication:
Denmark
Language:
English