POTENTIAL ANTIRADIATION DRUGS. II. /cap beta/-AMINOMERCAPTANS DERIVED FROM D-ALLOSE
Journal Article
·
· Journal of the American Chemical Society (U.S.)
A complex neighboring group approach provided a suc cessful synthesis of methyl 3-amino-2,3-dideoxy-2mercapto- alpha -D-allopyranoside hydrochloride(IX). The blocked 3-aminoaltroside(II) afforded, in two steps, the crystalline dithiocarbamovl mesylate(VI) which, heated in pyridine, cyclized to the thiazoline V, that was reduced to the thiazolidine IV. Compound IV was deblocked and hydrolyzed, via the crystalline mercuric salt VIII, to the aminomercapto glycoside IX. (auth)
- Research Organization:
- Stanford Research Inst., Menlo Park, Calif.
- Sponsoring Organization:
- USDOE
- NSA Number:
- NSA-15-032059
- OSTI ID:
- 4838856
- Journal Information:
- Journal of the American Chemical Society (U.S.), Journal Name: Journal of the American Chemical Society (U.S.) Vol. Vol: 83; ISSN JACSA
- Country of Publication:
- Country unknown/Code not available
- Language:
- English
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