EFFECTS OF FEEDING X-IRRADIATED PORK TO RATS, ON THEIR THIAMINE NUTRITION AS REFLECTED IN THE ACTIVITY OF ERYTHROCYTE TRANSKETOLASE

Journal Article · Fri Sep 01 04:00:00 EDT 1961 · J. Nutrition

OSTI ID:4830306

Brin, M; Ostashever, A S; Tai, M; Kalinsky, H

Chemical analysis showed that thiamine was destroyed to the extent of 92 and 98% in Pork exposed to ionizing radiations at levels of 2.79 and 5.58 megarad, respectively. Unirradiated pork, when incorporated into diets at 35% on a dry weight basis contained sufficient thiamine to support normal growth and normal erythrocyte transketolase ac tivity in rats. X-irradiated pork, unsupplemented with thiamine, resulted in growth retardation of rats to the extent of 53 and 63% and a depression of erythrocyte transketolase to the extent of 83 and 94% (on a hexose basis) when fed to rats at 35% of the diet on a dry weight basis for a 4-week feeding period. Treatment of the rats fed the diet containing irradiated pork with thiamine hydrochloride resulted in a rapid resumption of the normal growth rate and a concomitant increase in erythrocyte transketolase activity. (auth)

• Research Organization: Food and Drug Research Labs., Inc., Maspeth, N.Y.
• NSA Number: NSA-16-019221
• OSTI ID: 4830306
• Journal Information: J. Nutrition, Journal Name: J. Nutrition Vol. Vol: 75
• Country of Publication: Country unknown/Code not available
• Language: English

Related Subjects

AMINES
DIET
EFFICIENCY
ENZYMES
HEMOGLOBIN
INDUSTRIAL APPLICATIONS OF ISOTOPES AND RADIATIONS
IRRADIATION
MEAT
QUALITATIVE ANALYSIS
RATS
THIAMINE
TRANSKETOLASES
VITAMIN B-1
VITAMINS
X RADIATION