EFFECTS OF FEEDING X-IRRADIATED PORK TO RATS, ON THEIR THIAMINE NUTRITION AS REFLECTED IN THE ACTIVITY OF ERYTHROCYTE TRANSKETOLASE
Chemical analysis showed that thiamine was destroyed to the extent of 92 and 98% in Pork exposed to ionizing radiations at levels of 2.79 and 5.58 megarad, respectively. Unirradiated pork, when incorporated into diets at 35% on a dry weight basis contained sufficient thiamine to support normal growth and normal erythrocyte transketolase ac tivity in rats. X-irradiated pork, unsupplemented with thiamine, resulted in growth retardation of rats to the extent of 53 and 63% and a depression of erythrocyte transketolase to the extent of 83 and 94% (on a hexose basis) when fed to rats at 35% of the diet on a dry weight basis for a 4-week feeding period. Treatment of the rats fed the diet containing irradiated pork with thiamine hydrochloride resulted in a rapid resumption of the normal growth rate and a concomitant increase in erythrocyte transketolase activity. (auth)
- Research Organization:
- Food and Drug Research Labs., Inc., Maspeth, N.Y.
- NSA Number:
- NSA-16-019221
- OSTI ID:
- 4830306
- Journal Information:
- J. Nutrition, Vol. Vol: 75; Other Information: Orig. Receipt Date: 31-DEC-62
- Country of Publication:
- Country unknown/Code not available
- Language:
- English
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