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STERILIZATION OF DRUGS IN AMPOULES BY $gamma$-RAYS

Journal Article · · Acta Polon. Pharm.
OSTI ID:4822047
A Co/sup 60/ gamma -ray source was used to sterilize cocarboxylase hydrochloride (dried) contaminated by (1) bacteria and spores of C. welchii, (2) C. septicum, and (3) E. coli bacteria. A quantity of energy equivalent to 4 x 10/ sup 5/ rep was sufficient to sterilize the preparation and not cause any decomposition. In order to kill the same bacteria in an aqueous suspension, unsporing E. coli required 8 x 10/sup 5/ rep, and sporing C. welchii and C. septicum required 1.6 x 10/sup 6/ rep. (OID)
Research Organization:
Originating Research Org. not identified
NSA Number:
NSA-16-023424
OSTI ID:
4822047
Journal Information:
Acta Polon. Pharm., Journal Name: Acta Polon. Pharm. Vol. Vol: 18
Country of Publication:
Country unknown/Code not available
Language:
English

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