Study of the mechanism of innate resistance to virus infection
Journal Article
·
· Journal of Cellular and Comparative Physiology
The concept of genetically-determined natural resistance was explored in two mouse strains of different genetic origin exposed to West Nile encephalitis virus and yellow fever virus. The inheritance of virus resistance was studied by the cross-breeding of virus-resistant male mice with virus-susceptible mice of the other strain. Data are tabulated and results are discussed. The mechanism of natural resistance appeared to be expressed at the cellular level in a cell type described as the macrophage.
- Research Organization:
- Wistar Inst. of Anatomy and Biology, Philadelphia
- Sponsoring Organization:
- USDOE
- NSA Number:
- NSA-16-021951
- OSTI ID:
- 4815298
- Journal Information:
- Journal of Cellular and Comparative Physiology, Vol. 59, Issue 3; Other Information: Orig. Receipt Date: 31-DEC-62; ISSN 0095-9898
- Country of Publication:
- Country unknown/Code not available
- Language:
- English
Similar Records
SJL bone marrow-derived macrophages do not have IRF3 mutations and are highly susceptible to Theiler's virus infection
Crystal Structure of West Nile Virus Envelope Glycoprotein Reveals Viral Surface Epitopes
Presence of Viral RNA and Proteins in Exosomes from Cellular Clones Resistant to Rift Valley Fever Virus Infection
Journal Article
·
Fri Dec 15 00:00:00 EST 2017
· Virology
·
OSTI ID:4815298
Crystal Structure of West Nile Virus Envelope Glycoprotein Reveals Viral Surface Epitopes
Journal Article
·
Sun Jan 01 00:00:00 EST 2006
· Journal of Virology
·
OSTI ID:4815298
+6 more
Presence of Viral RNA and Proteins in Exosomes from Cellular Clones Resistant to Rift Valley Fever Virus Infection
Journal Article
·
Thu Feb 11 00:00:00 EST 2016
· Frontiers in Microbiology
·
OSTI ID:4815298
+5 more