POLAROGRAPHIC AND VOLTAMETRIC DETERMINATION OF PURINES AND PYRIMIDINES. ANALYSIS OF MIXTURES. Report No. 66

Technical Report · Fri Sep 15 04:00:00 EDT 1961

OSTI ID:4804038

Smith, D L; Elving, P J

The analytical significance and applicability is discussed of the polarographic and voltametric behavior at the dropping mercury electrode and at the stationary graphite electrode of purine and pyrimidine, and of a number of their derivatives, including those of biological and medicinal lmportance. The conditions are outlined under which one purine or pyrimidine can be determined in the presence of related compounds. To illustrate the possible analysis of mixtures, a procedure is given for the determination of the three most important nucleic acid components, i.e., adenine, cytosine and guanine, in the presence of each other. The qualitative potentialities of the electroactivity of the purines and pyrimidines is indicated, e.g., the identification of the three hydroxy- purines, hypoxanthine, xanthine, and uric acid, in the presence of each other. (auth)

• Research Organization: Michigan. Univ., Ann Arbor
• NSA Number: NSA-16-006370
• OSTI ID: 4804038
• Report Number(s): TID-14465
• Country of Publication: United States
• Language: English

Related Subjects

ADENINE
ALKALOIDS
BIOLOGY
CHEMISTRY
CYTOSINE
DRUGS
ELECTRIC METERS
ELECTRIC POTENTIAL
ELECTRODES
GRAPHITE
GUANINE
HETEROCYCLICS
HYDROXIDES
HYPOXANTHINE
KETONES
MEDICINE
MERCURY
MIXING
NUCLEIC ACIDS
ORGANIC COMPOUNDS
ORGANIC NITROGEN COMPOUNDS
PERFORMANCE
POLAROGRAPHY
PURINES
PYRIMIDINES
QUANTITATIVE ANALYSIS
XANTHINES