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U.S. Department of Energy
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ENZYMATIC AND BIOCHEMICAL STUDIES OF EPIDERMIS WHICH HAS BEEN IRRADIATED WITH BETA PARTICLES. Progress Report, February 1, 1961-January 1, 1962

Technical Report ·
OSTI ID:4803546
The effects of 300-, 600-, and 3000-rep beta doses on epidermal nucleases, viz. an acid DNase (DNase II, pH range 4.5 to 5.0) and a basic DNase (DNase I, pH 7.4), are examined. The effects of these irradiations on the relative epidermal concentrations of extracellular and cell-bound Mg/sup 2+/, on the epidermal concentrations of urea, ammonia, and free amino acids, and on skin tumor incidence are also studied. Optimal conditions are found for determinations of epidermal DNase I and DNase II, phosphatases, adenosine5'- nucleotidase, adenosine-5'-deoxyribonucleotidase, adenosine triphosphatase, and thymidine-5'-monophosphatase. The catabolism of purine and pyrimidine compounds is investigated. (T.F.H.)
Research Organization:
Albert Einstein Medical Center, Philadelphia
NSA Number:
NSA-16-012882
OSTI ID:
4803546
Report Number(s):
TID-14882
Country of Publication:
United States
Language:
English