THE POSSIBLE USE OF IONIZING RADIATION FOR THE STERILIZATION OF CERTAIN BIOLOGICAL PREPARATIONS. I. THE INFLUENCE OF IONIZING RADIATION UPON GAS-GANGRENE AND TETANUS ANTI-SERUM (SEROLOGICAL AND ELECTROPHORETIC INVESTIGATION)

Journal Article · Fri Dec 01 00:00:00 EST 1961 · J. Microbiol., Epidemiol. Immunobiol. (U.S.S.R.) (English Translation)

OSTI ID:4802840

Goncharenko, I M

The antltoxic properties and the relative proportion of the protein fractions of gas-gangrene and tetanus antisera were studied. The results show that the sterilization of dried antisera with gamma rays caused no marked decrease in the antitoxin titre. Similar results were obtained with liquid antisera containing 0.3% mercamine. However, crude and concentrated liquid antisera after sterilization by radiation showed a marked decrease in antitoxin titre. Under the usual conditions, sterilization of liquid antisera appears to be inadvsable, not-withstanding the simpliclty, convenience, and reliabillty of the method; sterilization of dried antisera, however, offers better prospects. (P. C.H.)

• Research Organization: Gamaleya Inst. of Epidemiology and Microbiology, U.S.S.R.
• NSA Number: NSA-16-007460
• OSTI ID: 4802840
• Journal Information: J. Microbiol., Epidemiol. Immunobiol. (U.S.S.R.) (English Translation), Vol. Vol: 32; Other Information: Orig. Receipt Date: 31-DEC-62
• Country of Publication: Country unknown/Code not available
• Language: English

Related Subjects

BIOLOGY AND MEDICINE
AMINES
ANTIBODIES
BACTERIA
BLOOD SERUM
GAMMA RADIATION
IMMUNITY
LIQUIDS
MEA
ORGANIC SULFUR COMPOUNDS
PROTEINS
QUANTITY RATIO
RADIATION EFFECTS
STERILIZATION
THIOLS