HOMOTRANSPLANTATION OF SKIN AND FETAL HEMATOPOIETIC TISSUE IN LETHALLY IRRADIATED MICE
Journal Article
·
· Japan J. Exptl. Med.
OSTI ID:4801047
Skin homotransplantations were performed in the mice that were restored by the administration of homologous fetal hematoponetie tissues after lethal whole-body irradiation. Three different strains of inbied mice were used for recipients, donors of skin homografts, and donors of fetal hematopoietic tissues. The prolongation of the survival times of the skin homografts was observed until 60 days, in maximum, after the transplantation. The mechanism of the prolongation and a hypothesis of tolerance are discussed on the basis of the principles of both actively acquired tolerance and radiation chimera. (auth)
- Research Organization:
- Tokyo Univ.
- NSA Number:
- NSA-16-011492
- OSTI ID:
- 4801047
- Journal Information:
- Japan J. Exptl. Med., Journal Name: Japan J. Exptl. Med. Vol. Vol: 31
- Country of Publication:
- Country unknown/Code not available
- Language:
- English
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