THE EFFECT OF OXYGEN CONCENTRATION ON THE FREQUENCY OF INDUCED XO MALES AND NON-DISJUNCTION FEMALES AFTER IRRADIATION OF DROSOPHILA MALES

Journal Article · Sun Jan 01 04:00:00 EST 1961 · Hereditas (Sweden)

OSTI ID:4789553

Saevhagen, R

Studies were made on the effect of irradiation under different oxygen concentrations during various stages of spermatogenesis. By use of a dual purpose stock it was possible to study the frequency of induced XO males and induced non-disjunction between the paternal X and Y chromosomes. Drosophila, 0- 1 and 3-4 day old y/sup 16/ and sc/sup 8/Y males, were irradiated in commercial nitrogen or oxygen and mated to virgin y w sn females. A comparison between the yield of XO males after irradiation under anaerobic conditions and the corresponding data after treatment in air shows that a significantly lower rate of induced XO males is obtained after irradiation in N/sub 2/ atmosphere. The difference is most marked in mating periods corresponding to the period of highest sensitivity. The effect of commercial oxygen on the frequency of induced XO males after irradiation of 0-1 and 3-4 day old males is reversed as compared to the effect of air atmosphere. For 3-4 day old males irradiation in O/sub 2/ increases the yield of XO males. For both types of males almost no enhancing effect is obtained for mature spermatozoa after irradiation in O/sub 2/. it is concluded that it is not possible to talk about a common air/nitrogen ratio of radiosensitivity for irradiated Drosophila males, since there exists great variations between the different mating periods. For 3-4 day old males, irradiation under anoxia gives an almost total protection against induced non- disjunction. For 0-l day old males a reduction in the yield of non-disjunction females is observed, but still on the 8th day a rise in wild type females was observed. The relation between radiosensitivity and intra and/or intercellular oxygen available in the treated cells is discussed. (P.C.H.)

• Research Organization: Univ. of Stockholm
• NSA Number: NSA-16-017467
• OSTI ID: 4789553
• Journal Information: Hereditas (Sweden), Journal Name: Hereditas (Sweden) Vol. Vol: 47; ISSN HEREA
• Country of Publication: Country unknown/Code not available
• Language: English

Related Subjects

AGE
ANIMAL CELLS
BIOLOGY AND MEDICINE
CHROMOSOMES
DROSOPHILA
GENETICS
GONADS
INSECTS
IRRADIATION
NITROGEN
OXYGEN
QUANTITY RATIO
RADIATION EFFECTS
RADIOSENSITIVITY
SEX