The absorption of calcium, strontium, barium and radium from the gastrointestinal tract of the rat

Journal Article · Sun Apr 01 04:00:00 EST 1962 · Biochemical Journal

DOI:https://doi.org/10.1042/bj0830025· OSTI ID:4786264

TAYLOR, DM; BLIGH, PH; DUGGAN, MH

>The absorption of Ca, Sr, Ba, and Ra from the gastrointestinal tract of the rat was studied by means of double radioactive tracer techniques. At 14-18 days of age there is almost complete absorption of calcium and strontium and about 80% of barium and radium is absorbed. For animals 6- 8-weeks old absorption of Ca decreased to about 60%, Sr to 25%, Ba to 7% and Ra to 11%. In animals at 60-70 weeks of age the absorption of all the elements except barium is decreased to between one-third and onehalf of these levels. Deprivation of food before administration markedly increases the absorption of barium and radium and slightly reduces calcium absorption. Administration of the elements in cow's milk significantly enhances the absorption of calcium and, more particularly, strontium in 6-8-week-old rats. The absorption of barium and radium is not affected and the effect is not observed in old animals. The results for the absorption of barium and radium show a closer similarity to each other than to the results for strontium and calcium. (auth)

• Research Organization: Royal Cancer Hospital, London
• Sponsoring Organization: USDOE
• NSA Number: NSA-16-017416
• OSTI ID: 4786264
• Journal Information: Biochemical Journal, Journal Name: Biochemical Journal Journal Issue: 1 Vol. 83; ISSN 0264-6021
• Publisher: Biochemical Society
• Country of Publication: Country unknown/Code not available
• Language: English

Related Subjects

ABSORPTION
AGE
BARIUM
BIOLOGY AND MEDICINE
CALCIUM
FOOD
INTESTINE
MILK
RADIUM
RATS
STOMACH
STRONTIUM
TRACER TECHNIQUES