THE BIOLOGICAL PROTECTION OF SKELETAL-MUSCLE TISSUE AGAINST INJURY BY IONIZING RADIATION

Journal Article · Sun Jul 01 04:00:00 EDT 1962 · Doklady Akad. Nauk S.S.S.R.

OSTI ID:4786176

Studitskii, A N; Popova, M F

Pulverized muscle tissue transplanted to an open cut car serve as a protective agent against damage bv ionizing radiation. Muscle was removed from both extremities of a white rat, and was cut up with scissors. Part of the ground muscle was put back in the cut. Numerous previous experiments showed that regeneration of muscle tissue in this type of cut was impossible without introduction of the pulverized muscle tissue. The regenerating muscle tissue was then given a local x-ray dose of 2000 r in 24 hours, 3 days, 7 days, and 21 days after the operation. In the control ani mals the muscle tissue was removed, subjected to pulverization, and transplanted after the irradiation. The control tive tissue but only an insignificant development of muscle tissue in the cut. The ground muscle tissue did not show any signs of development in the first few days, but after 3, 7, and 21 days a rapid development of miogenic tissue by mitotic division is observed. The regenerative processes going on in the damaged tissue protect the muscle tissue from damage by ionizing radiation. The regenerating tissue is resistant to radiation damage, and continues its development without noticeable deviation from the norm. (TTT)

• Research Organization: Severtsov Inst. of Animal Morphology, USSR
• NSA Number: NSA-16-030230
• OSTI ID: 4786176
• Journal Information: Doklady Akad. Nauk S.S.S.R., Journal Name: Doklady Akad. Nauk S.S.S.R. Vol. Vol: 145
• Country of Publication: Country unknown/Code not available
• Language: Russian

Related Subjects

ANIMAL CELLS
BIOLOGY AND MEDICINE
MITOSIS
MUSCLES
RADIATION DOSES
RADIATION INJURIES
RADIATION PROTECTION
RATS
REGENERATION
SURGERY
TRANSPLANTS
X RADIATION