THE EFFECTS OF RADIATIONS ON THE GENETIC SYSTEMS OF ORGANISMS IN RELATION TO THEIR PHYSIOLOGICAL AND BIOCHEMICAL SYSTEMS. Progress Report, May 1, 1958-April 30, 1959

Technical Report · Thu Oct 31 04:00:00 EST 1963

OSTI ID:4774061

Alexander, M L

The developing germ cells of Drosophila virilis were used as a biological system for the comparison radiation damage in dividing and several types of non-dividing cells. By utilizing different radiations, cell types, and environmental controls, the variations in radiosensitivity of nondividing cells were shown to depend both on differences in sensitivity of the chromosomes for breakage and differences in enhancement of biological damage from environmental changes. A differential action upon cells in division and non-dividing cells was shown. Preliminary studies indicate that several lethal actions resulting from treatment of dividing cells can be separated and tested with the various radiations. Data are included on the effects of radiations from fission neutrons, accelerator neutrons, therapy x rays, gamma rays from a Co/sup 60/ source, and 22-Mv x rays from a betatron accelerator. Germ cells of varying sensitivities were exposed in an atmosphere of oxygen or nitrogen. Data are presented graphically. Results are included from a study of mutation rates at specific gene loci in mature sperm and spermatogonial cells of Drosophila melanogaster. (C.H.)

• Research Organization: Texas. Univ., Houston. M.D. Anderson Hospital and Tumor Inst.
• NSA Number: NSA-17-001237
• OSTI ID: 4774061
• Report Number(s): TID-17001
• Country of Publication: United States
• Language: English

Related Subjects

ACCELERATORS
AGE
ANIMAL CELLS
BETATRONS
BIOLOGY
BIOLOGY AND MEDICINE
CHROMOSOMES
COBALT 60
DROSOPHILA
DROSOPHILA MELANOGASTER
ENVIRONMENT
FISSION PRODUCTS
GAMMA RADIATION
GENETICS
GONADS
INSECTS
LETHAL DOSE
MITOSIS
MUTATIONS
NEUTRONS
NITROGEN
OXYGEN
RADIATION EFFECTS
RADIATION INJURIES
RADIOSENSITIVITY
RADIOTHERAPY
SPERMATOGONIA
X RADIATION