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COMPARATIVE RESISTANCE OF STRAINS OF CLOSTRIDIUM BOTULINUM TO GAMMA RAYS

Journal Article · · Applied Microbiology (U.S.) Changed to Appl. Environ. Microbiol.ed as Arch. Pathol. (March 1928-September 1950 and July 1960-December 1975) and as AMA
OSTI ID:4771852

A total of 102 strains of Clostridium botulinum (56 strains of type A, 43 type B, and 3 non-toxigenic strains which could not be typed) was examined for resistance to gamma rays. When the organisms were suspended in neutral phosphate buffer in concentrations of 10/sup 4/ spores per tube, the threshold sterilizing dose appeared to be 1.4 Mrad. Partial survival to 1.4 Mrad was shown by 10.7 f the type A strains, 18.6% of the type B strains, and 1 of 3 nontoxigenic strains. Overall, type A strains indicated higher radioresistance than type B strains, although there was overlapping. Representatives of the most resistant strains had D values of 0.317 to 0.336 Mrad; the D values of an intermediate group were 0.224 to 0.253 Mrad, and the most sensitive strain studied, 51B, had a D value of 0.129 Mrad. The radioresnstance of Putrefactnve Anaerobe 3679, strain S - 2, was comparable to the intermediate C. botulinum group (D = 0.209). (Public Health Eng. Abstr., 42: No. 11, Nov. 1962)

Research Organization:
U.S. Army Quartermaster Food and Container Inst., Chicago
NSA Number:
NSA-17-004394
OSTI ID:
4771852
Journal Information:
Applied Microbiology (U.S.) Changed to Appl. Environ. Microbiol.ed as Arch. Pathol. (March 1928-September 1950 and July 1960-December 1975) and as AMA, Journal Name: Applied Microbiology (U.S.) Changed to Appl. Environ. Microbiol.ed as Arch. Pathol. (March 1928-September 1950 and July 1960-December 1975) and as AMA Vol. Vol: 10; ISSN APMBA
Country of Publication:
Country unknown/Code not available
Language:
English