HISTOLOGIC ASPECTS OF OCULAR HYPERTONIA INDUCED BY ROENTGEN IRRADIATION

Journal Article · Sat Jul 15 04:00:00 EDT 1961 · Boll. Soc. Ital. Biol. Sper.

OSTI ID:4768290

Cecio, A; Menna, F

Elevated intraocular pressure sometimes follows x-ray therapy directed toward the eye. To investigate the pathogenesis of this disorder, adult guinea pigs were given a single 1400 r dose, either over the whole body or directed toward the iridocorneal angle. Local irradiation resulted in detachment of corneal epithelium, interruption of the normal trabecular structure of the ciliary process, and confluence of the lymphatic lacunae of Fontana. At a later stage, blood vessels and ciliary muscle show injury. After whole-body irradiation similar changes were seen in the ciliary body, which incurred more injury than other ocular structures. It is suggested that the primary damage to the eye resulting in increased intraocular pressure occurs here. Since the ciliary body is responsible for formation of ocular fluid and regulation of its exchange, disruption of its function by irradiation injury may result in increased pressure of this fluid. (H.H.D.)

• Research Organization: Universita, Naples
• NSA Number: NSA-17-005794
• OSTI ID: 4768290
• Journal Information: Boll. Soc. Ital. Biol. Sper., Journal Name: Boll. Soc. Ital. Biol. Sper. Vol. Vol: 37
• Country of Publication: Country unknown/Code not available
• Language: English

Related Subjects

AGE
BIOLOGY AND MEDICINE
CORROSION
EYES
FLUIDS
FLUORINE
GASES
GUINEA PIGS
LYMPH SYSTEM
RADIATION DOSES
RADIATION INJURIES
RADIOTHERAPY
SODIUM CARBONATES
SODIUM SULFIDES
SOLUTIONS
SPUTTERING
STORAGE
VESSELS