Effect of Irradiation and Test System on Development of Tetanus Antibodies

Journal Article · Fri Mar 01 04:00:00 EST 1963 · Experimental Biology and Medicine

DOI:https://doi.org/10.3181/00379727-112-28095· OSTI ID:4725838

Benenson, A. S.; Shively, J. N.; Vivona, S.

Whole-body irradiation of dogs immunized with an alum precipitated tetanus toxoid results in a delay in appearance of antitoxin of the first toxoid us administered after radiation. Dogs irradiated 30 days after a first dose of toxoid and receiving a booster injection 24 hours after irradiation presented a good antitoxin response when measured by the hemagglutination test. However, a poor antibody response was found if the antitoxin was measured by the toxin neutralization techniques.

• Research Organization: Walter Reed Army Inst. of Research, Washington, D.C.
• Sponsoring Organization: USDOE
• NSA Number: NSA-17-023137
• OSTI ID: 4725838
• Journal Information: Experimental Biology and Medicine, Journal Name: Experimental Biology and Medicine Journal Issue: 3 Vol. 112; ISSN 1535-3702
• Country of Publication: Country unknown/Code not available
• Language: English

Related Subjects

62 RADIOLOGY AND NUCLEAR MEDICINE
ANTIBODIES
BACTERIA
BODY
DOGS
ERYTHROCYTES
IMMUNITY
INFECTIONS
MEASURED VALUES
PRECIPITATION
RADIATION DOSES
RADIATION EFFECTS
TESTING
TETANUS
TOXICITY
VARIATIONS