Effects of Different Ionizing Radiations on Human Cells in Tissue Culture. III. Experiments with Cyclotron-Accelerated Alpha-Particles and Deuterons
Experiments are described in which cells of human origin in tissue culture were irradiated with alpha -particles of kev/ of tissue, respectively) and with deuterons of 3.5, 6.3, and 14.9-Mev energy (LET 17.4, 11.0, and 5.8 kev/ of tissue, respectively). Damage to the reproductive capacity was measured by counting the fraction of cells that developed into clones of more than 50 cells after irradiation. With densely ionizing particles an exponential dosesurvival was obtained, whereas with sparsely ionizing radiation a partly exponential, partly cumulative type of curve was obtained. The RBE as a function of LET was determined for various levels of damage. The implications of the results are discussed.
- Research Organization:
- TNO, Rijswijk, Netherlands
- Sponsoring Organization:
- USDOE
- NSA Number:
- NSA-17-023157
- OSTI ID:
- 4725799
- Journal Information:
- Radiation Research, Journal Name: Radiation Research Journal Issue: 1 Vol. 18; ISSN 0033-7587
- Publisher:
- Radiation Research Society
- Country of Publication:
- Country unknown/Code not available
- Language:
- English
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