EFFECT OF DIFFERENT DIETS ON THE SECRETORY FUNCTION OF THE INTESTINE IN DOGS SUFFERING FROM EXPERIMENTAL RADIATION SICKNESS
A study was made of the effects of different fats on the secretory function of the digestive glands in dogs irradiated with 400 r and operated with isolated duodenal sections. The diet contained 18% protein, 52% carbohydrates, and 30% fats, such as beef fat, sunflower-seed, cottonseed, or linseed oil. This was given one month before and one month after irradiation. The controls were fed beef fat. After irradiation, the liquid portion of the intestinal juice increased, and from the 9th and 10th day on, lasting in some cases to 10 to 12 weeks. The feeding of unsaturated fatty acids had no influence on these factors. Enrichment of the vegetable oils with 8% of highly unsaturated arachidonic acid reduced both the hypersecretion and the intensity and duration of intestinal hemorrhage; the general reaction to irradiation then became weaker and the rate of survival higher. A daily addition of 25 mg of pyridoxine to linseed oil produced a similar effect while the dogs fed with the control diet showed no reaction to pyridoxine. The ferment content of the intestinal juice changed only when arachidonic acid was given (distinct increase in enterokinase); after irradiation it was not affected by the diet. (OTS)
- Research Organization:
- Originating Research Org. not identified
- NSA Number:
- NSA-17-019925
- OSTI ID:
- 4720173
- Journal Information:
- Vopr. Pitaniya, Journal Name: Vopr. Pitaniya Vol. Vol: 21: No. 6
- Country of Publication:
- Country unknown/Code not available
- Language:
- English
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